ID A0A3B3HDK5_ORYLA Unreviewed; 250 AA.
AC A0A3B3HDK5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
GN Name=LOC101174977 {ECO:0000313|Ensembl:ENSORLP00000029886.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000029886.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000029886.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000029886.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000029886.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000029886.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
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DR AlphaFoldDB; A0A3B3HDK5; -.
DR Ensembl; ENSORLT00000045669.1; ENSORLP00000029886.1; ENSORLG00000030546.1.
DR GeneTree; ENSGT00940000155929; -.
DR InParanoid; A0A3B3HDK5; -.
DR Proteomes; UP000001038; Chromosome 13.
DR Bgee; ENSORLG00000030546; Expressed in brain and 9 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR GO; GO:0017080; F:sodium channel regulator activity; IBA:GO_Central.
DR CDD; cd00058; FGF; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF156; FIBROBLAST GROWTH FACTOR; 1.
DR Pfam; PF00167; FGF; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 250 AA; 28339 MW; 42C504AF588E069D CRC64;
MAAAIASSLI RQKRQARESN NNQVASSKRR SSPSKDPRSL CERHVFSVFR KVRFCSGKKR
PVRRKPEPQL KGIVTRLFSE QGFFLQMLPD GTISGCKDEN SDHTLFNLIP VGLRVVAIQG
VKAGLYVAMN AEGFLYTSDV FTPECKFKES VFENYYVIYS STLYRQHESG RAWFLGLNKE
GIIMKGNRVK KTKPCSHFVP RPIEVCMYKE PSLHELEEKL LKSSRSPTTD PPPTPHPLDS
AGIPRKRSSF
//
