ID A0A3B3HG19_ORYLA Unreviewed; 865 AA.
AC A0A3B3HG19;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=F-box protein 11a {ECO:0008006|Google:ProtNLM};
GN Name=fbxo11a {ECO:0000313|Ensembl:ENSORLP00000030723.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000030723.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000030723.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000030723.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000030723.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000030723.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3HG19; -.
DR STRING; 8090.ENSORLP00000030723; -.
DR Ensembl; ENSORLT00000038994.1; ENSORLP00000030723.1; ENSORLG00000011053.2.
DR GeneTree; ENSGT00530000063425; -.
DR InParanoid; A0A3B3HG19; -.
DR Proteomes; UP000001038; Chromosome 15.
DR Bgee; ENSORLG00000011053; Expressed in animal zygote and 14 other cell types or tissues.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd22091; F-box_FBXO11; 1.
DR CDD; cd19676; UBR-box_UBR6_FBXO11; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 4.
DR InterPro; IPR039448; Beta_helix.
DR InterPro; IPR006633; Carb-bd_sugar_hydrolysis-dom.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR047505; F-box_FBXO11.
DR InterPro; IPR047504; FBXO11_UBR-box.
DR InterPro; IPR022441; Para_beta_helix_rpt-2.
DR InterPro; IPR006626; PbH1.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR003126; Znf_UBR.
DR NCBIfam; TIGR03804; para_beta_helix; 5.
DR PANTHER; PTHR22990; F-BOX ONLY PROTEIN; 1.
DR PANTHER; PTHR22990:SF20; F-BOX ONLY PROTEIN 11; 1.
DR Pfam; PF13229; Beta_helix; 2.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF02207; zf-UBR; 1.
DR SMART; SM00722; CASH; 3.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00710; PbH1; 19.
DR SMART; SM00396; ZnF_UBR1; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF51126; Pectin lyase-like; 3.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS51157; ZF_UBR; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 91..137
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT DOMAIN 771..842
FT /note="UBR-type"
FT /evidence="ECO:0000259|PROSITE:PS51157"
FT ZN_FING 771..842
FT /note="UBR-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00508"
FT REGION 53..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 865 AA; 96739 MW; 3287289FB1CE1C13 CRC64;
MKSQRCNHFL HLPPRVDEDI PAEMVAEESG PGAQNSPYQL RRKSLPKRTV CPTKTNMEGA
STSTIENFGH RPKRPRVSGK CQDLPVAPAE QYLQEKLPDE VVLKIFSYLL EQDLCRAACV
CKRFGELAND PILWKRLYME VFEYTRPMMH PEAGKFYQIN PEEYEQPNPW KESFQQLYKG
AHVKPGFAEH FYSNPARYKG RDNMFYYDTI EDALGGGQEP HFDGLIFVHS GIYTDEWIYI
ESPITMIGAA AGKVAEKVII ENTRDSTFVF MEGSEDAFVG YMTIRFNPDD KSAQHHNAHH
CLEITVNCSP IIDHCIIRST CTVGSAVCVS GQGACPKIKH CNISDCENVG LYITDHAQGI
YEDNEISNNA LAGIWVKNHG NPIIRRNHIH HGRDVGVFTF DHGMGYFESC NIHRNRIAGF
EVKAYANPTV VRCEIHHGQT GGIYVHEKGR GQFIENKIYA NNFAGVWITS NSDPTIRGNA
IFNGNQGGVY IFGDGRGLIE GNDIYGNALA GIQIRTNSCP IVRHNKIHDG QHGGIYVHEK
GQGVIEENEV YSNTLAGVWV TTGSTPVLRR NRIHSGKQVG VYFYDNGHGV LEDNDIYNHM
YSGVQIRTGS NPKIRRNKIW GGQNGGILVY NSGLGFIEDN EIFDNAMAGV WIKTDSNPTL
RRNKIHDGRD GGICIFNGGR GLLEENDIFR NAQAGVLIST NSHPVLRKNR IFDGFAAGIE
ITNHATATLE GNQIFNNRFG GLFLASGVNV TMKDNKILNN QDAIEKAVSR GQCLYKISSY
TSYPMHDFYR CHTCNTTDRN AICVNCIKKC HQGHDVEFIR HDRFFCDCGA GTLSNPCTLA
GEPTHDTDTL YDSAPPIESN TLQHN
//
