ID A0A3B3HI12_ORYLA Unreviewed; 639 AA.
AC A0A3B3HI12;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Heat shock protein 8 {ECO:0000313|Ensembl:ENSORLP00000031332.1};
GN Name=hspa8 {ECO:0000313|Ensembl:ENSORLP00000031332.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000031332.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000031332.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000031332.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000031332.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000031332.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR AlphaFoldDB; A0A3B3HI12; -.
DR Ensembl; ENSORLT00000043351.1; ENSORLP00000031332.1; ENSORLG00000013520.2.
DR GeneTree; ENSGT00950000183206; -.
DR Proteomes; UP000001038; Chromosome 14.
DR Bgee; ENSORLG00000013520; Expressed in gastrula and 14 other cell types or tissues.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR CDD; cd10233; HSPA1-2_6-8-like_NBD; 1.
DR Gene3D; 1.20.1270.10; -; 1.
DR Gene3D; 3.30.30.30; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR PANTHER; PTHR19375:SF379; HEAT SHOCK COGNATE 71 KDA PROTEIN; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT REGION 603..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 70448 MW; 57B703A834D8FE82 CRC64;
MLIGYPAPYM FFDQTFAFFT LLVPVTVAFA LRCLRFPNTH FRPPTICFGS MSKGPAVGID
LGTTYSCVER LIGDAAKNQV AMNPTNTVFD AKRLIGRRFD DHVVQSDMKH WPFNVINDNT
RPKVQVEYKG ETKSFYPEEI SSMVLTKMKE IAEAYLGKTV NNAVITVPAY FNDSQRQATK
DAGTISGLNV LRIINEPTAA AIAYGLDKKV GSERNVLIFD LGGGTFDVSI LTIEDGIFEV
KSTAGDTHLG GEDFDNRMVN HFIAEFKRKY KKDISDNKRA VRRLRTACER AKRTLSSSTQ
ASIEIDSLYE GVDFYTSITR ARFEELNADL FRGTLDPVEK SLRDAKMDKG QIHDIVLVGG
STRIPKIQKL LQDFFNGKEL NKSINPDEAV AYGAAVQAAI LSGDKSENVQ DLLLLDVTPL
SLGIETAGGV MTVLIKRNTT IPTKQTQTFT TYSDNQPGVL IQIEVTFDID ANGIMNVSAV
DKSTGKENKI TITNDKGRLS KEDIERMVQE AEKYKAEDDV QRDKVSAKNG LESYAFNMKS
TVEDEKLAGK ISDEDKQKIL DKCNEVISWL DKNQTAERDE YEHQQKELEK VCNPIITKLY
QSAGGMPGGM PEGMPGGFPG AGGAAPGGGS SGPTIEEVD
//
