ID A0A3B3HKX1_ORYLA Unreviewed; 879 AA.
AC A0A3B3HKX1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=CUB and zona pellucida-like domains 1, tandem duplicate 1 {ECO:0008006|Google:ProtNLM};
GN Name=cuzd1.2 {ECO:0000313|Ensembl:ENSORLP00000032342.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000032342.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000032342.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000032342.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000032342.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000032342.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR AlphaFoldDB; A0A3B3HKX1; -.
DR Ensembl; ENSORLT00000044582.1; ENSORLP00000032342.1; ENSORLG00000005563.2.
DR GeneTree; ENSGT00940000165331; -.
DR Proteomes; UP000001038; Chromosome 15.
DR Bgee; ENSORLG00000005563; Expressed in intestine and 4 other cell types or tissues.
DR CDD; cd00041; CUB; 2.
DR Gene3D; 4.10.410.20; -; 3.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR Gene3D; 2.60.40.3210; Zona pellucida, ZP-N domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR036024; Somatomedin_B-like_dom_sf.
DR InterPro; IPR001212; Somatomedin_B_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR14002:SF38; DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN-LIKE-RELATED; 1.
DR PANTHER; PTHR14002; ENDOGLIN/TGF-BETA RECEPTOR TYPE III; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF01033; Somatomedin_B; 1.
DR Pfam; PF00100; Zona_pellucida; 1.
DR SMART; SM00042; CUB; 2.
DR SMART; SM00201; SO; 8.
DR SMART; SM00241; ZP; 1.
DR SUPFAM; SSF90188; Somatomedin B domain; 8.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS00524; SMB_1; 6.
DR PROSITE; PS50958; SMB_2; 8.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..879
FT /note="CUB and zona pellucida-like domains 1, tandem
FT duplicate 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017274212"
FT DOMAIN 39..78
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 84..127
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 129..168
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 174..213
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 225..331
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 332..375
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 377..420
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 421..461
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 465..504
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 500..621
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 630..843
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
SQ SEQUENCE 879 AA; 97681 MW; 7F0FFCE2DDD5FF58 CRC64;
MWTLIFLCIV LATQDASATG AEKLRAYYTE TAYTEAATEQ PSCRYNCGYD MGSCSCTSHC
EYYGNCCYDY SSHCQTTTGE SATAQPSCRY NCGSHLGSCS CSSSCQYYGN CCYDYSSYCQ
TTTGEPATAQ PSCRYNCGSH LGSCSCSSSC QYYGNCCYDY SWQCSSTAES PATTQSSCQY
NCGSYQGSCS CSSSCEYHGN CCDDYYSYCS STTDQQATDV TVGPCGGDFY NSSDTFYSPN
YPNHYHNNAN CIWYIRPSRG IVQLEFSNVD IECSYDNIRV YDGSSTGSRL LGTYCSSRNT
IFYSTGRHLT VHFTSDGIVT FSGFSAYYRV VDEGSCQHNC DYQVGNCSCS SWCRDRGDCC
WDYEAYCQTT TGEPTTAQPS CRYNCGSHLG SCSCSSSCQY YGNCCYDYYD HCYTTHSPVT
AEQSCRDMCG SYPGGCSCYS DCEYYGSCCH DYYNYCQTAP AHTTAQPTCR YNCGSHQGSC
SCYSSCEHYG NCCHDYYSYC AASTPSPSGP CGGSLFGSGT FSSPNYPSYY YDNSYCVWQL
RASHDQRIYL ALTFLQLENC CSCDHISVYD GPSIHSPQLG RVCNNNTSLS AFFSTSNYMT
VVFQTDGSVV ARGFTAEFLS SLKPNSGRVD CSSDSMHIVL DRSYLNSLGY DGHSLYLRDP
YCRPQISYYN VVFSFPLNTC GNVRDVMNDR IVYTNNIYAY SSINGEITRQ SQFKMNVTCI
MEQDSISQIM FVADTGLNTT ITGSGRYNTS MDFYTSSSFY NKVTQVPYEV SVNENLPYFL
VKDGCPVDST YYSISSGSQP LARFSFKAFQ FLRATDEVYI QCKVLICPAS DYNSRCRRGC
RRRNKRSLGS NHDSHTLVVG PIKLKELKGE EGAEKQSEA
//
