ID A0A3B3HMQ0_ORYLA Unreviewed; 286 AA.
AC A0A3B3HMQ0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=SplA/ryanodine receptor domain and SOCS box containing 4a {ECO:0000313|Ensembl:ENSORLP00000033045.1};
GN Name=LOC101156850 {ECO:0000313|Ensembl:ENSORLP00000033045.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000033045.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000033045.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000033045.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000033045.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000033045.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the SPSB family.
CC {ECO:0000256|ARBA:ARBA00010910}.
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DR RefSeq; XP_011484949.1; XM_011486647.1.
DR AlphaFoldDB; A0A3B3HMQ0; -.
DR Ensembl; ENSORLT00000026965.1; ENSORLP00000033045.1; ENSORLG00000013981.2.
DR GeneID; 101156850; -.
DR KEGG; ola:101156850; -.
DR GeneTree; ENSGT01030000234629; -.
DR OrthoDB; 65989at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000001038; Chromosome 17.
DR Bgee; ENSORLG00000013981; Expressed in brain and 11 other cell types or tissues.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03718; SOCS_SSB1_4; 1.
DR CDD; cd12906; SPRY_SOCS1-2-4; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR12245; SPRY DOMAIN CONTAINING SOCS BOX PROTEIN; 1.
DR PANTHER; PTHR12245:SF3; SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 44..244
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 234..286
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 286 AA; 32271 MW; 7F7C56229C179EFE CRC64;
MGQKISGGIK SVDGRGESGA SPSYRPTAHR RQHLELRGPD FSRPPRLDLL LDMPCVGVET
QLRHAWNPDD RSLNIFIKDD DKLTFHRHPV AQSTDCIRGR VGYTRGLHVW NIHWPARQRG
THAVVGVATA EAPLHSVGYT ALVGSDSESW GWDLGRNRLY HDSKNRAHSS LPSYPCFLEP
EETFILPDSL LVILDMDEGT LSFMVDGQYL GVAFRGLKGK KLYPIVSAVW GHCEISMRYI
NGLDPEPLPL MDLCRRAARL ALGRDRLQEI ERLPLPQSLK NYLQYQ
//
