ID   A0A3B3HQ99_ORYLA        Unreviewed;      1130 AA.
AC   A0A3B3HQ99;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000033962.1, ECO:0000313|Proteomes:UP000001038};
RN   [1] {ECO:0000313|Ensembl:ENSORLP00000033962.1, ECO:0000313|Proteomes:UP000001038}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000033962.1,
RC   ECO:0000313|Proteomes:UP000001038};
RX   PubMed=17554307; DOI=10.1038/nature05846;
RA   Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA   Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA   Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA   Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA   Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA   Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT   "The medaka draft genome and insights into vertebrate genome evolution.";
RL   Nature 447:714-719(2007).
RN   [2] {ECO:0000313|Ensembl:ENSORLP00000033962.1}
RP   IDENTIFICATION.
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000033962.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3HQ99; -.
DR   STRING; 8090.ENSORLP00000033962; -.
DR   Ensembl; ENSORLT00000040101.1; ENSORLP00000033962.1; ENSORLG00000028428.1.
DR   GeneTree; ENSGT00940000163438; -.
DR   InParanoid; A0A3B3HQ99; -.
DR   Proteomes; UP000001038; Chromosome 2.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR35450; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR35450:SF2; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT   DOMAIN          401..676
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1130 AA;  129103 MW;  7926DFDF72C23CB7 CRC64;
     MNHVMPAQTS PGQTRSASGA EGPGHPDGKW ATGTRRKWTR CENKVLLECY YSSNPTQRGY
     MQRMWNEWML RNPQSRLTAK QLVAQCSNIH KRQLLLQLEI EAIQYNATGE PEQQVREEVM
     PHSLPEIGYT APTTTITLSE AATDLKDKIM STMNTRQPRH QLQRLSDVPE SLLETVNEAL
     RAIPTTTISE TNELVYTSAA VILEMLGYKS NHGRKQYPPW KQRLEAKIKA TRKDVSKLTE
     AQRGTMRKQV PKRYSQMPIP EALETAKQRL LALSSPLKRY TRDNEARRIN RLFATQPAKV
     YTQWQGQNSR ADPPRLETEQ YWKSIWEKQT AHKQTAQWLV SLRKEHSNLP EQNPVTITVA
     DIQERVSGMK NWTAPGPDMI HVYWLKKLTA LHECLAAQMN QLLRDGTHPE WLTEGRTILI
     QKDPSKGAIP SNYRPITCLY TTWKLMSGII ATKINRHMDQ FMSNTQKGIG RDSRGAKHQL
     LVDRTVAQDC KSRHTNLCTA WIDYKKAYDS MPHTWITECL ELYNINRTLR AFIENSMKLW
     KTTLEANGKP LAQVSIKCGI YQGDALSPLL FCIGLNPLSQ IITKTGYGYR LRNGANISHL
     LYMDDIKLYA KSERDIDSLI HTTRIYSTDI GMSFGLEKCS RMVTKRGKVV HTGGVSLPEG
     TIADIEDSYK YLGIPQANGN LEQATRKAAT AKYLQRVRQV LRSQLNGKNK TRATNSYALP
     VIRYPAGLIR WPKEEIQTRD VKTRKLLTMH GGFHPKSSTL RLYASRKEGG RGLVSVEATI
     QDETSKMHEY IKLKAPTDSV LSECLRQWRA ENTVLEDRSS WEDKPLHGMY HRTITEVADI
     KKSYQWLERA GLQDSTEALI LAAQEQALST RAIEAQIYYT RQDPRCRLCK EAPETIQHIT
     AGCKMLAGKA YMERHNQVAG IVYRNMCAEY ELETPRSKWE TPPKVVENER AKILWDFQIQ
     TDRMVMENRP DIVVVDKEQR KAVVVDVAVP SDGNIRKKEH EKLEKYQGIR EELEKAWKVK
     VTVVPVVIGA LGAVTPKLEE WLQHIPGKTS DLSVQKRTGT AEILQDPQAP RPLVEDPSLE
     EKPPAEGERG IFYIFFFTGV HGLHEIFPPL FTFFMVGRTT QWKGGVIWTP
//