ID A0A3B3HQI6_ORYLA Unreviewed; 483 AA.
AC A0A3B3HQI6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Olfactomedin 1a {ECO:0000313|Ensembl:ENSORLP00000034159.1};
GN Name=olfm1b {ECO:0000313|Ensembl:ENSORLP00000034159.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000034159.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000034159.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000034159.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000034159.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000034159.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. Synapse
CC {ECO:0000256|ARBA:ARBA00034103}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004074575.1; XM_004074527.2.
DR AlphaFoldDB; A0A3B3HQI6; -.
DR Ensembl; ENSORLT00000036077.1; ENSORLP00000034159.1; ENSORLG00000025343.1.
DR GeneID; 101160252; -.
DR KEGG; ola:101160252; -.
DR CTD; 445092; -.
DR GeneTree; ENSGT00940000156959; -.
DR InParanoid; A0A3B3HQI6; -.
DR OMA; EYKADAQ; -.
DR OrthoDB; 2876896at2759; -.
DR Proteomes; UP000001038; Chromosome 12.
DR Bgee; ENSORLG00000025343; Expressed in brain and 12 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR InterPro; IPR022082; Noelin_dom.
DR InterPro; IPR003112; Olfac-like_dom.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR PANTHER; PTHR23192:SF34; NOELIN; 1.
DR PANTHER; PTHR23192; OLFACTOMEDIN-RELATED; 1.
DR Pfam; PF12308; Noelin-1; 1.
DR Pfam; PF02191; OLF; 1.
DR SMART; SM00284; OLF; 1.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR PROSITE; PS51132; OLF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00446}; Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..483
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017290705"
FT DOMAIN 226..478
FT /note="Olfactomedin-like"
FT /evidence="ECO:0000259|PROSITE:PS51132"
FT COILED 94..142
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 178..224
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 227..409
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00446"
SQ SEQUENCE 483 AA; 55139 MW; 90EF9C5F1A6B1766 CRC64;
MSVPLLKIGV VLSTMAMITN WMSQTLPSLV GLNTTKLTAA QGGYLDRSTG VLPANPEESW
QVFSSAQDSE GRCVCTVVAP QQSMCSRDAR TKQLRQLLEK VQNMTQSIQV LDQRTQRDLQ
YVEKMEVQLR GLETKFRQVE ENHKQNIAKQ YKAIKAKMEE LRPLIPVLEE YKADAQLVLK
FKEEVQNLTS VLSELQEEMG AYDYEELHNR VSNLEERLRA CMQKLACGKL TGISEPITIK
ISGSRFGSWM TDPLAPEGDT RVWYMDGYHN NRFVREYKSM HDFMTSDNFT SHRLPHPWSG
TGQVVYNGSI YFNKFQSHVI IKFDFRTSSI SKSRQLESAG FNNAYHYAWG GHSDIDLMVD
EGGLWAVYAT NQNAGNIVIS KLNPNTLQII KSWTTNHPKR SAGESFMICG TLYVTNSYSG
GTKVYYAYST NSSTYEYIDI AFQNKYSHIS MLDYNPHDRA LYAWNNGHQV LYNVTLFHVI
RSE
//
