ID A0A3B3HR82_ORYLA Unreviewed; 897 AA.
AC A0A3B3HR82;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000034255.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000034255.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000034255.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000034255.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000034255.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B3HR82; -.
DR Ensembl; ENSORLT00000031103.1; ENSORLP00000034255.1; ENSORLG00000028420.1.
DR GeneTree; ENSGT01100000263527; -.
DR InParanoid; A0A3B3HR82; -.
DR Proteomes; UP000001038; Chromosome 9.
DR Bgee; ENSORLG00000028420; Expressed in pharyngeal gill and 7 other cell types or tissues.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR46670; ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46670:SF3; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 427..702
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 897 AA; 102008 MW; 3230886F0CE60830 CRC64;
MFLTETWQKE EEFIHLNELC LEGCSVIGKP RPSRRGGGVA VVYKDNYTCK DMNTQTFSSF
ESLSFKVDTS DPFYCVLVYR PPGPAAPFLH DFSDFLSSII KLERVLILGD FNLHINDCSS
CPAMEFLFLT ETFNFEQHVS DPTHQKGNTL DLVFSLGLSI TNLYVEDVHM SDHSGVFFEL
NVTPEPVSSC ILSQRRIITA NTDGRFSALF DPHLFKECSD VNNLIDRFSD HCVTILDQVA
PVKSNLSKKK VCPWINEAIQ NLKRQCRQTE RLLKSTNLMV HRLHLRDLVS SYNEMVKDAR
SNYFRQLISS NKKSPKVLFD TINSIVGPAA PVPPVFCKAD SNEFLKFFAN KTKKIKEQLP
PPCCDEGVVV EPVSHKWSTF RPVTLEDISA LLTKLKPSTC PSDVIPSKLF LKVFETIGQS
VTEMINLSLS TGVFPNAFKH AIVEPLLKKS NLDPSVFQNY RPISKLPFIS KILEKVVAEQ
LSEFLDKRSI YDTFQSGFRK HHSTETALLK VSSDILMSAD SGRHTVLVLL DLSSAFDTVD
HQILLDRLRD LIGLSGSVLH WFSSYLSGRN FSVMANHKMS QSVDLLCGVP QGSVLGPVLF
LLYMIPLGKI IQDFSDVSYH LFADDIQLYC SFKPSETHKL DSLMNCLMQI KQWLCKNSLQ
LNSEKTETLV VAPDDAIPGI KQHLGSLGQD VKPSLRNLGV IFDKDMSLEQ HSKQLIRNCF
FQLRNISKLR KMVSYEDLEL LIHAFVSTRL DYCNSLFSCL NKKELSRLQL IQNSAARILT
RTKRRDHISP ILKALHWLPV AYRYQYKILV LTFRALHSQA PPYVCDLIAP YRPSRALRSA
DQNLLMVPRT RFRTRGDRSF QAVAPKLWNE LPLSLRSLDS VNSFKSQLKT FYFCKAF
//
