ID A0A3B3HTJ6_ORYLA Unreviewed; 120 AA.
AC A0A3B3HTJ6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Eukaryotic translation initiation factor 4E binding protein 1 {ECO:0008006|Google:ProtNLM};
GN Name=LOC101165490 {ECO:0000313|Ensembl:ENSORLP00000034658.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000034658.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000034658.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000034658.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000034658.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000034658.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eIF4E-binding protein family.
CC {ECO:0000256|ARBA:ARBA00005480}.
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DR RefSeq; XP_004074908.1; XM_004074860.2.
DR AlphaFoldDB; A0A3B3HTJ6; -.
DR STRING; 8090.ENSORLP00000034658; -.
DR Ensembl; ENSORLT00000028469.1; ENSORLP00000034658.1; ENSORLG00000028190.1.
DR GeneID; 101165490; -.
DR KEGG; ola:101165490; -.
DR GeneTree; ENSGT00940000159932; -.
DR InParanoid; A0A3B3HTJ6; -.
DR OrthoDB; 2911937at2759; -.
DR Proteomes; UP000001038; Chromosome 12.
DR Bgee; ENSORLG00000028190; Expressed in liver and 14 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0008190; F:eukaryotic initiation factor 4E binding; IBA:GO_Central.
DR GO; GO:0045947; P:negative regulation of translational initiation; IBA:GO_Central.
DR InterPro; IPR008606; EIF4EBP.
DR PANTHER; PTHR12669; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN; 1.
DR PANTHER; PTHR12669:SF14; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1; 1.
DR Pfam; PF05456; eIF_4EBP; 1.
PE 3: Inferred from homology;
KW Protein synthesis inhibitor {ECO:0000256|ARBA:ARBA00023193};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT REGION 63..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 120 AA; 13041 MW; CA2484A166649047 CRC64;
MSAGGQTTTS LEIPAVRRVA IHDAAHMPHE YSTTPGGTLF STTPGGTRII YERKFLLQCR
TSPLARTPPN NLPDIPGVTR PLNSDSSHDT KNPVEAPTTN NHDTDVQTEE GEDAQFEMDI
//
