ID A0A3B3HTS7_ORYLA Unreviewed; 1768 AA.
AC A0A3B3HTS7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=LIM and calponin homology domains 1a {ECO:0008006|Google:ProtNLM};
GN Name=LOC101155575 {ECO:0000313|Ensembl:ENSORLP00000035160.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000035160.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000035160.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000035160.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000035160.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000035160.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSORLT00000040181.1; ENSORLP00000035160.1; ENSORLG00000007835.2.
DR GeneTree; ENSGT00950000183159; -.
DR Proteomes; UP000001038; Chromosome 1.
DR Bgee; ENSORLG00000007835; Expressed in bone element and 11 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08368; LIM; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR031865; DUF4757.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR15551:SF3; LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR15551; LIM DOMAIN ONLY 7; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF15949; DUF4757; 2.
DR Pfam; PF00412; LIM; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM00132; LIM; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 26..143
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1696..1762
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 169..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 552..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 871..901
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1034..1063
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1118..1343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1415..1459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1498..1530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1551..1690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 669..701
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 170..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..208
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..431
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..523
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..901
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 933..955
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1159..1342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1415..1438
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1445..1459
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1502..1529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1551..1571
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1576..1612
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1651..1680
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1768 AA; 196365 MW; 0956B94C21DFA444 CRC64;
MASPAACKTL SSAPPRALLE ANHHPEPACL EAQKWIEAVT GKCFGDKDFR SALENGILLC
ELLSAIKPGL VRKINRLPTP IAGLDNLTVF LRGCEELGLK GSQLFDPGDL QDTSIRANLK
DSDCNRKLKN VLNTVFWLGK AASGCAFYSG PTLNLKEFEG LLAQMRVESD DGATSPQNRS
VRDSGYDCWD SERSESLSPP RHTRDNSLDS LDSFGSRSQH SPSPDVGNRG ASDGRGSDSE
ADGPGRKPDV RKDDMLARRT ASSESRSSIP FNQFLPNRNN ATAYIPTPRR KMSTEEGEQR
SHSQAIPEQT KRTGQHNKAP KTVTWAPENN GEKPKQEEQM VTQETLEQRK LQKLEKAGIK
VLPAAVHHIS PATIKEKETS SEPPSIILRC ENDFMNFCKT AWDSSSDGEE EGEKRKVPDV
RKDDLASRRG RRGPTTAKVH QFVPSPECTN KDMERWEGIR RASQQTLQDK DISGKEAVPD
IITRRDNPFL KEKEEVSDEG KEVEAVPNKQ RDDLARRRAQ SRPLPQRDAQ MSFVTSSMSQ
ADVQRWERLK MTEPSEDRPA PVCQACLEKN DGRPHGRPAK AGRGHSKVVT FGGVTEIKQP
VDTVMGSEWE ENKLLRRLLS VATVAVPAID LGSQLSEREH SHIDGVEPDQ ATLPSADVQP
WTPEATPTVA ELDARLALYE QRAEEEEEEE EEERIPDLQK DDMMARRTGV FQKQSAASAA
FSRFLPLPGS KRCMQEEVNT NKLLKFKNDA NEVKHLDLNV RPKHQNPKVP AETAQQHQEF
TVTRTASLSL SEKEQDPAVP DLEKDDMMAR KARLFQKGSA LKTNQSFNQF LPVPGSAKYN
ASPVSAVKLP QSRPVLAESF GSSVSVAAEH QIPFKDPTGP THAGARGRQE GEDQEKGDTM
RATDTIVSKV TESPPSPALA LPAHSCSRVV EAEQQMETER TDAEEGKKGV NEKTQKKPFW
LEDELPPIMV SRRVAFLLNN ESVSMTDMVN EEEAGHLPLL SQSRHERMHE QYNNFQEEED
HWQDDLARWK SRRRSASQEL IRKEEERKRM EKMKEERRDG HKRKSIKTYK EIVEEKERRE
AELCEAYRNA ATPEEAALVL QRYALRFTIS DATLDSLKLP RSTSKPKHDL NGTTQEDKPA
SPVNGSEMLE HLPKPKPASL NQKHTNPENM ETDVIQELEK SGATSSSSTT SNSPVSADTN
SQIVPPQSPQ FCKPTTQFTE SAATNQKDLN SGDTLLQSKH ISFQDAQEQS QTMQPQFPQS
QPTQSKPVQL QLAQPQSEQL QPTQPQSEQP TQSQLEQPQP AQSRSEQLQP AQSEQLQPAQ
SQLEQLQPVQ SHIEQLQPAQ PHSEHLQRVI YTQPIHTLPS PAPARPVPML VAKPYCQPRT
TLKPVKMDGL VRVNGEMMED SVVSPSPSAL LDSLQEKQEN KDVSSKQAEE DNPPEEAVEN
PKTAEQLTPP PQNEKTAAAA TSAISSLIGG RSCTITTTIV TELTQTLVEP LYPEIQSNKK
TPIEEKTQPP ASPSNKQKYS PTVTDGLEES CVTEQYLREQ EKLKKEWEKA QIEVEEEERK
HNEEERRILE ETVTPLSPTG LLQQGSGHTA VSAPAPENNN KGEGNVSLEQ NGKKVPTGRE
DQHASKLHFF QDSACDGQPS KRPEPWKTAS LDRNPQLSQT QNVKRSGSHD AVTGEQQSSP
STPQPPSPSR CVSGKRLCSG CSKPLGKGAA MIIDTLGLYF HMGCFKCGVC KGQLGDASAG
TDVRIRNGQL SCHECYIASR GRGQPTTL
//
