ID A0A3B3HVF2_ORYLA Unreviewed; 960 AA.
AC A0A3B3HVF2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000035819.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000035819.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000035819.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000035819.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000035819.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3HVF2; -.
DR Ensembl; ENSORLT00000036228.1; ENSORLP00000035819.1; ENSORLG00000028622.1.
DR GeneTree; ENSGT01090000260066; -.
DR InParanoid; A0A3B3HVF2; -.
DR Proteomes; UP000001038; Chromosome 10.
DR Bgee; ENSORLG00000028622; Expressed in testis and 7 other cell types or tissues.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR46670; ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46670:SF3; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 491..765
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 960 AA; 108559 MW; CFEF1B20681F6C30 CRC64;
MQKRAVRLSN QRNLVHIPCK KVLTSPKETN LKLAALNVRS LCNKSFLINN LISSFNLDFM
FLTETWLDKN TGNIVLVEST PPNYKHESEI RENKKGGGVS ALFRDNIATR RLSFGMFSSF
EYVSFKIELK QTPPLLCIVM YKPPQHSQSF IDDFTEMLSV VCTDFDGLVI TGDFNVHVDN
VNDRNAKELN AVLETFSLIQ HMSCPTHSRG HTLDLLITRG VTIYNVSVVD VALSDHFCVF
FDLSVAPKPP PGPAVVQRRQ INESTRAQFV EMINPENVSG ANVDEMLNSV TSSILNVQDA
IAPMKVQLRK HRQKAPWRND DLVRAQKQQC RRAERKWRKS KLQVHYGIYK AELYAYNQIL
CRTRERYFSE IIGSCSSNSR ILFTTVNRLT NPPTQLPIEL VCTPKCNEFA VLFNDKVQGI
KKAINSTTHI TIERPPTHSK LTHFIPVTDQ TVQETITRLS SSTCCLDVLP TRFLKSVLNS
VLPSITQIVN MSLQSGIFPE ALKTAVIKPL LKKSGLDPTV LNNYRPISNL PFLGKVLEKV
VYQQLTDFLL LNNSFDVFQS GFRPHHSTET ALIKVTNDIR LNTDDGKVSV LILLDLSAAF
DTVDHGILLH RLQDWVGISG SALSWLKSYL EDRKYFVEIG SCVSDYMGLN CGVPQGSILG
PLLFNLYMLP LGQLIRSNNI SYHNYADDTQ IYVSLTTGEY GPVDSLNHCL QQISAWMQNN
FLQLNSDKTE VIVFGPHKQR EIVSSYLHSL SLKPSNQVRN LGVIMDSDLN FNSHIKSVTS
AAFYHLKNIA KIKNIISKRD LEILIHAFVS SRLDYCNGLL TGLSKRAVKQ LQSIQNAAAR
VLTKTRKYDH ISPVLRSLHW LPVPQRIDFK AALLVYKSLH GRAPKYISDM LVPYEPSRTL
RTSGTGLLLI PRVRTKQGES AFQYSAAKIW NSLPEVVRQA SSVFMFKSRL KTFLFSRVYD
//
