ID A0A3B3HWW4_ORYLA Unreviewed; 781 AA.
AC A0A3B3HWW4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Terminal nucleotidyltransferase 4A {ECO:0000313|Ensembl:ENSORLP00000036106.1};
GN Name=TENT4A {ECO:0000313|Ensembl:ENSORLP00000036106.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000036106.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000036106.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000036106.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000036106.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000036106.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3HWW4; -.
DR STRING; 8090.ENSORLP00000036106; -.
DR Ensembl; ENSORLT00000041943.1; ENSORLP00000036106.1; ENSORLG00000025175.1.
DR GeneTree; ENSGT00940000157811; -.
DR InParanoid; A0A3B3HWW4; -.
DR OrthoDB; 21395at2759; -.
DR Proteomes; UP000001038; Chromosome 11.
DR Bgee; ENSORLG00000025175; Expressed in ovary and 14 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0031499; C:TRAMP complex; IBA:GO_Central.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:InterPro.
DR GO; GO:0031123; P:RNA 3'-end processing; IBA:GO_Central.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR045862; Trf4-like.
DR PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR PANTHER; PTHR23092:SF24; TERMINAL NUCLEOTIDYLTRANSFERASE 4A; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 267..371
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 430..489
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 58..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 185..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 560..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 710..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..633
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 710..724
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 725..762
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..781
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 781 AA; 85239 MW; F721C7E8071A1F7C CRC64;
MDPRVAWIQP EQKGPANTLW MYVWETSQGG RTLSAPVQFH NQNHNQCVNY AAAAAEKNGA
PSKSSGDGAA TAGRSGGHHG FTNGINASCK DSSTRTSDHP AEENTVLQKA GSVSSSSSQE
SGTDVFASSC LPERTIGANV SGNLNQNVGG ANMLFGLNDG VESNGNLHHL PQEHQTLHPQ
QVCARRLRGP PPHSQHPGRR KSDNKASTYG MTYLLSICTH GGHASTMTPW KTMTYSAGIR
GLHEEVMDFY KYMSPRPEEA AMRKEVVKRI ETIIKEQWPS ADVQIFGSFS TGLYLPTSDI
DLVVFGKWER PPLQELEQAL RKHNVAEPFS IKVLDKATVP IIKLTDQETE VKVDISFNVE
TGVKAASFIK DYVKKYPVLP YLIFVLKQFL LQRDLNEVFT GGISSYSLIL MVISFLQLHP
RINARNPNEN LGMLLIEFFE LYGRHFNYLK TGIRIRNGGA YMAKEEMMKA MTNGYRPSML
CIEDPLLPGN DVGRGSYGAM QVKQVFDYAY AILSHAVSPL ARSYPNKDCE STLGRIIRLT
QEVIDYREWI IKKWGGKDSV QTDNRGLSPK EPAPKESSVL SGGGAGAEEQ QRDSASPYSA
DSPMSISSPQ QHSSASSVSS LSGSDNDSDS ALPCPLPQPT VPAYPSFPPT GLALPACINM
GSGKPCMGGH HLLLPAGSQT RVSLPAGLAV HAMPGRQVCM HTGLPHFFHM PPPAPAPSSP
QLPPSPHSSH NQKNGAKFNG KGFHNPSLVN SVAVANRGHT QYPRNSWRRR KRDSLPVSLS
R
//
