ID A0A3B3HY22_ORYLA Unreviewed; 320 AA.
AC A0A3B3HY22;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSORLP00000036323.1};
GN Name=LOC111948934 {ECO:0000313|Ensembl:ENSORLP00000036323.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000036323.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000036323.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000036323.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000036323.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000036323.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CALHM family.
CC {ECO:0000256|ARBA:ARBA00008497}.
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DR STRING; 8090.ENSORLP00000036323; -.
DR Ensembl; ENSORLT00000030905.1; ENSORLP00000036323.1; ENSORLG00000026639.1.
DR Ensembl; ENSORLT00000046297.1; ENSORLP00000037787.1; ENSORLG00000026639.1.
DR GeneTree; ENSGT01030000234610; -.
DR Proteomes; UP000001038; Chromosome 16.
DR Bgee; ENSORLG00000026639; Expressed in pharyngeal gill and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005261; F:monoatomic cation channel activity; IBA:GO_Central.
DR InterPro; IPR029569; CALHM.
DR PANTHER; PTHR32261; CALCIUM HOMEOSTASIS MODULATOR PROTEIN; 1.
DR PANTHER; PTHR32261:SF4; CALCIUM HOMEOSTASIS MODULATOR PROTEIN 6; 1.
DR Pfam; PF14798; Ca_hom_mod; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 47..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 320 AA; 35761 MW; 6B4874C7D8CB05D3 CRC64;
MEKFQAILKF ASKQTNFGYG LVALITACGE QIFSSVAFKC PCNELNFIYG LVFLLMPALA
LLLLGIILSK KTWKLTTGFC HRNSKLCNWR NLKSMGVTVF QISASALVAP STWIAVALLH
GSYYECAMTG ANSTSYTEVV CRGVNFEAKC VTELQTFPCR NTGNEIEEIL RTVRAHSQIL
GWLVIASIMI SNLLVICVAH CFSPISYLQL KFWKNYAEEE NDLMNDYSSK HAKELADRNL
KSFFNQDPAG NIVTPCNKDW EKISSLYKFS TKDHFYSTLH RYIENKDDTG GSMRLASLRS
NESANNPPVL DFVDGGTAAL
//
