ID A0A3B3HZ77_ORYLA Unreviewed; 474 AA.
AC A0A3B3HZ77;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Forkhead box J1a {ECO:0000313|Ensembl:ENSORLP00000036891.1};
GN Name=foxj1a {ECO:0000313|Ensembl:ENSORLP00000036891.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000036891.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000036891.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000036891.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000036891.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000036891.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- SIMILARITY: Belongs to the FOXJ1 family.
CC {ECO:0000256|ARBA:ARBA00034770}.
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DR AlphaFoldDB; A0A3B3HZ77; -.
DR STRING; 8090.ENSORLP00000036891; -.
DR Ensembl; ENSORLT00000041887.1; ENSORLP00000036891.1; ENSORLG00000001276.2.
DR GeneTree; ENSGT00940000164514; -.
DR InParanoid; A0A3B3HZ77; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000001038; Chromosome 8.
DR Bgee; ENSORLG00000001276; Expressed in testis and 7 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd20023; FH_FOXJ1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR047512; FH_FOXJ1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR047513; FOXJ1.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46805; FORKHEAD BOX PROTEIN J1; 1.
DR PANTHER; PTHR46805:SF1; FORKHEAD BOX PROTEIN J1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 3: Inferred from homology;
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 151..245
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 151..245
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 26..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 474 AA; 51186 MW; A585A1248D32C2F4 CRC64;
MLSLSCADPW PEGSVVLEEE VVTAAAQAEE RDAAGSCSSS SSSSSSSSSS SSSWCGSDNL
DDSLTSLQWL QDFSILGANV PQHAHQQPHF FGQQLGLDAP ASPLAGDPAS MGMPLTPGKP
TAASYSRIQP GVVARGLTPD GADYRNNARV KPPFSYATLI CMAMQASKKS KITLSCIYKW
ITDNFCYYRH ADPTWQNSIR HNLSLNKCFI KVPRQKDEPG KGGFWKIDPQ YAEHLLSGSH
KKRRMPPVQI NPALQSRLHI HLQPRSSTPC PLADGLDFNP HAPSLMQGLE EVTGADQSWN
PRLAEGTMLG AWPVVRGRRG KKRKNPFGSR NGGTRGFRGS SSPLLCGEEQ KQVGPLEGDF
DWDALLDSAL SGELSLDEEG PLSPILKEEA LTARGGQVAA GEAPAGTTAD QRSNVPDFDE
ETLLATAFLE TPWPGEEEEE QSQANFLCNS NLDQLFDLGD SLHGDPSGQM DPLL
//
