ID A0A3B3I2I8_ORYLA Unreviewed; 559 AA.
AC A0A3B3I2I8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=TSC22 domain family member 2 {ECO:0000313|Ensembl:ENSORLP00000038028.1};
GN Name=TSC22D2 {ECO:0000313|Ensembl:ENSORLP00000038028.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000038028.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000038028.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000038028.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000038028.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000038028.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TSC-22/Dip/Bun family.
CC {ECO:0000256|ARBA:ARBA00007908}.
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DR RefSeq; XP_011472282.1; XM_011473980.1.
DR AlphaFoldDB; A0A3B3I2I8; -.
DR Ensembl; ENSORLT00000029882.1; ENSORLP00000038028.1; ENSORLG00000007302.2.
DR GeneTree; ENSGT00940000160465; -.
DR Proteomes; UP000001038; Chromosome 4.
DR Bgee; ENSORLG00000007302; Expressed in pharyngeal gill and 14 other cell types or tissues.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd21941; ZIP_TSC22D4; 1.
DR Gene3D; 1.20.5.490; Single helix bin; 1.
DR InterPro; IPR000580; TSC22/Bun.
DR InterPro; IPR047862; TSC22/BUN_CS.
DR PANTHER; PTHR46894; TSC22 DOMAIN FAMILY PROTEIN 2; 1.
DR PANTHER; PTHR46894:SF1; TSC22 DOMAIN FAMILY PROTEIN 2; 1.
DR Pfam; PF01166; TSC22; 1.
DR SUPFAM; SSF58026; Delta-sleep-inducing peptide immunoreactive peptide; 1.
DR PROSITE; PS01289; TSC22; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT REGION 28..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 471..505
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 182..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 559 AA; 59486 MW; 8C0A2B6B295469DC CRC64;
MSKMPGKRSC FQITSVTQAQ VAANCLPDDT ESQDDLDESR TGDMPPEGFD VCRVDQGACA
TNCSEEISHY GGDSLPNKAL VNGGFYLKSL ASGRLTPGMP PSNFAASSML TSVTQTAPSN
SYSSRFRVIK LDHGTGEPFR RGRWNCTEFY ERDSESNLTV DSLKSAVSLD YTDRESVLGA
TSNSFVSSST SSAQGLESTT DSGYFASVGH PSHSYHSESQ QQDYRLSPRK GSGASAFLPT
GLNGVHHGSR QQMPPSIPPA SQAQQLDYSA HPTGISDYHQ QQFSSGALTS SVVSSSGHVS
SPQISSPGPA KRRLGSETGS AQTVIAPIHT QQQPVSQPQL PGGLGIALPL FSTTSSNSGG
QNVPVSMPSA TSIPQGGSDP MSSSHGAAVH QPEDSRQKVD VLPQHISTVA RQDGVRTPIT
DGFDMQRSTV KNLFNIQISM DVDDDSASGA SAVAIDNKIE QAMDLVKSHL MYAVREEVEV
LKEQIKELYE RNSMLERENA VLKSLANTEQ LSQLTGPTSN SSTPVQQLHH LPLVANSPAS
LLHLEGSPSI PHQPNISSA
//
