ID   A0A3B3I7H4_ORYLA        Unreviewed;       535 AA.
AC   A0A3B3I7H4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSORLP00000039829.1};
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000039829.1, ECO:0000313|Proteomes:UP000001038};
RN   [1] {ECO:0000313|Ensembl:ENSORLP00000039829.1, ECO:0000313|Proteomes:UP000001038}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000039829.1,
RC   ECO:0000313|Proteomes:UP000001038};
RX   PubMed=17554307; DOI=10.1038/nature05846;
RA   Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA   Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA   Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA   Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA   Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA   Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT   "The medaka draft genome and insights into vertebrate genome evolution.";
RL   Nature 447:714-719(2007).
RN   [2] {ECO:0000313|Ensembl:ENSORLP00000039829.1}
RP   IDENTIFICATION.
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000039829.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B3I7H4; -.
DR   STRING; 8090.ENSORLP00000039829; -.
DR   Ensembl; ENSORLT00000033380.1; ENSORLP00000039829.1; ENSORLG00000022297.1.
DR   GeneTree; ENSGT00650000094113; -.
DR   InParanoid; A0A3B3I7H4; -.
DR   Proteomes; UP000001038; Chromosome 13.
DR   Bgee; ENSORLG00000022297; Expressed in pharyngeal gill and 13 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0000445; C:THO complex part of transcription export complex; IBA:GO_Central.
DR   GO; GO:0006406; P:mRNA export from nucleus; IBA:GO_Central.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   InterPro; IPR025307; FIIND_dom.
DR   InterPro; IPR021861; THO_THOC1.
DR   PANTHER; PTHR13265:SF1; CASPASE RECRUITMENT DOMAIN FAMILY MEMBER 8; 1.
DR   PANTHER; PTHR13265; THO COMPLEX SUBUNIT 1; 1.
DR   Pfam; PF00531; Death; 1.
DR   Pfam; PF13553; FIIND; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
DR   PROSITE; PS51830; FIIND; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT   DOMAIN          82..367
FT                   /note="FIIND"
FT                   /evidence="ECO:0000259|PROSITE:PS51830"
FT   DOMAIN          410..494
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          49..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        54..79
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   535 AA;  59994 MW;  5B9514A2E595C40A CRC64;
     MSNRFADNLS ESDSNSSGEH IYKAGKSFFI PALVSGRVSD IWIYLTDNHG TSTEDSSEED
     DEEEEEEEEG EEEEEEEGSG ERISLTGFIT TLIVNIGDSA LCFRVQLEAD VSYECSATGL
     VFEATEPVLV RYSILSWSKF AGFLGNSWKF AGPIFNVETV KKDASVLKSI QFPHCVCLAR
     KSNEGSSDMT FGILHVKGNR PLIEPTVDHS GSHVKWNVTS LSPVGPIIQT PQPVDRHGVV
     LVYKQLGSSL HNYSFHIYLA TNSASDIKDI AKQVRACKNR YIKIDKPPTC KLDEGTYRLL
     SEPEGDIKPQ ELNFTLAVTK MKGYFEAFFE QPPPFKLSLI ETNTEETVWS ATIREGTSIS
     MINLVFLIGL PSNPAGLPMS VTVYTEARKW AGISFLCSAC ILVTQDQSMS ERQLLLVANQ
     LGKEWKQVAI FLDWTSKELD NIQAAEKDVV MQKHKMLVGW KNRRRPGEAT AYHLWDSIKG
     LELPNEVYQI LRGKAQQINI TLNVFRIHSC LVLKSYRTAG HKHQVLKTQT CCKFR
//