ID A0A3B3I7W8_ORYLA Unreviewed; 699 AA.
AC A0A3B3I7W8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cap binding complex dependent translation initiation factor {ECO:0000313|Ensembl:ENSORLP00000040148.1};
GN Name=CTIF {ECO:0000313|Ensembl:ENSORLP00000040148.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000040148.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000040148.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000040148.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000040148.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000040148.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3I7W8; -.
DR STRING; 8090.ENSORLP00000040148; -.
DR Ensembl; ENSORLT00000045010.1; ENSORLP00000040148.1; ENSORLG00000005786.2.
DR GeneTree; ENSGT00940000153432; -.
DR InParanoid; A0A3B3I7W8; -.
DR OrthoDB; 2955689at2759; -.
DR Proteomes; UP000001038; Chromosome 12.
DR Bgee; ENSORLG00000005786; Expressed in gastrula and 14 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008494; F:translation activator activity; IBA:GO_Central.
DR GO; GO:0006446; P:regulation of translational initiation; IBA:GO_Central.
DR Gene3D; 1.25.40.180; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR23254:SF16; CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR; 1.
DR PANTHER; PTHR23254; EIF4G DOMAIN PROTEIN; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 471..676
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 45..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 245..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..388
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 77940 MW; 717A984AF0BD4591 CRC64;
MENSSVASAS SEAGSTRSQE IEELERFIDS YVLEYQVQGL LGDKADGELD LDSGDKMPQW
TEDCFDKRDG SWTSSQGRGS SKPDEWEHSS NGSTGSRPSS GSRQGSGSRS GSRGRNNQFK
APAKNGNKDG SFDILGTDIW AANTMDSRGG AGWDVQPEKL DFSHFHRKHL RGTPKHLPHI
DREGMNKNKF VEEDGIDMND IERFLPHLCS VFPPFPNDAE IAHTKKLFRR RRNDRRTFDH
FTRGQLTVLL PTGPGGKRQV SARKQQRPQG GGGGGGGGGG AKTLPQQIQQ QSPQLQWDRT
QQQYPNQPQQ TLTEPGENRH SRPPRQYQGG QRTAGPSHGY SQNRHHYQKG QGQGPTNAPW
EKGVPPRATK DKDTENVKVD DKQSRPLKQN DSSRSPNDSA RPDSTHSTDP LPDLIVRKEC
PNPQRGGKAS EGQSEQPKVS LLQSSKERLR GRLKDKEEAH VEKSQSGSQS LDRLVDLLNN
MRSNSSGVEQ QLASFMEEAQ CSAQSEESLA QVVSTIYSKA VSDRSFAATA AKLCDKMALF
MVEGTKFRSL LLNRLQKDFC RRGEIQQSDV EQWLGFITFL CEVFGTMRSS SGEPFRVLVC
PIYTCLRELL QSTDVKEDAV LCCSMELQSM GHLLEEQLPE MMTELLATVR DKMLCPAESE
LTRSLLMEVI ELHAHSWSPL EALTTQYYNR TIQKLTTSA
//
