ID A0A3B3IDL2_ORYLA Unreviewed; 636 AA.
AC A0A3B3IDL2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Synaptotagmin binding, cytoplasmic RNA interacting protein {ECO:0000313|Ensembl:ENSORLP00000041903.1};
GN Name=LOC101169504 {ECO:0000313|Ensembl:ENSORLP00000041903.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000041903.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000041903.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000041903.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000041903.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000041903.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; A0A3B3IDL2; -.
DR STRING; 8090.ENSORLP00000041903; -.
DR Ensembl; ENSORLT00000030974.1; ENSORLP00000041903.1; ENSORLG00000009190.2.
DR GeneTree; ENSGT00940000153511; -.
DR InParanoid; A0A3B3IDL2; -.
DR OrthoDB; 3184171at2759; -.
DR Proteomes; UP000001038; Chromosome 24.
DR Bgee; ENSORLG00000009190; Expressed in blastula and 14 other cell types or tissues.
DR GO; GO:0070937; C:CRD-mediated mRNA stability complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR GO; GO:0048027; F:mRNA 5'-UTR binding; IBA:GO_Central.
DR GO; GO:0070934; P:CRD-mediated mRNA stabilization; IBA:GO_Central.
DR CDD; cd21066; NURR_hnRNPQ; 1.
DR CDD; cd12250; RRM2_hnRNPR_like; 1.
DR CDD; cd12495; RRM3_hnRNPQ; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR041337; hnRNP_Q_AcD.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR PANTHER; PTHR21245:SF11; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Q; 1.
DR Pfam; PF18360; hnRNP_Q_AcD; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 170..242
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 251..333
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 346..416
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 497..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 636 AA; 70977 MW; 228D36F46945B874 CRC64;
MMSEEMATDQ VNGNGTEEAQ EPMDTTLAAT RSEHFQALLE AGLSQKVAEK LDNLYVAGLV
AHSDLDERAI EALKEFNEEG ALQVLVQFKE SDLSHVQNKS AFLCGVMKTY RQREKQGTKV
SRTSKGPDEA KIKELLDRTK YTLDVTTGQR KYGGPPPESV YSGPQPTVGT EIFVGKIPRD
LFEDELVPLF EKAGSIWDLR LMMDPLSSLN RGYAFVTFCA KEAAQEAVKL CNNYEIRPGK
HIGACISVAN NRLFVGSIPK SKTKEQIVEE FSKVTDGLND VILYHQPDDK KKNRGFCFLE
FEDHKTAAQA RRRLMSGKVK VWGILVTVEW ADPIEDPDPE VMAKVKVLFV RNLANSVTEE
ILEKSFSAFG KLERVKKLKD YAFIHFEERE GAVKALDEMN GKELEGEPIE IVFAKPPDQK
RKERKAQRQA AKTQIYDDYY YYPPAPHAPP ARGRGRGGNR GGYGYPSDYY SYDDYYDYYG
YDYHNYRGGY EDPYYGYEDF QSPSRGRGSS RGARGGTSPA RGRGSAGAPR GRPSFPPHGG
PGPSRGGRGA RGGVQPRGRG GVRGVRGGRG GNVGGKRKAD GYNQPDSKRR QTNNQNWGSQ
PIAQQPLQGG DHAGNYFGYK SDNQEFYQDS FGQQWK
//
