ID A0A3B3IFI5_ORYLA Unreviewed; 1944 AA.
AC A0A3B3IFI5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Myosin, heavy chain b {ECO:0008006|Google:ProtNLM};
GN Name=LOC101163631 {ECO:0000313|Ensembl:ENSORLP00000042903.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000042903.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000042903.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000042903.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000042903.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000042903.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR STRING; 8090.ENSORLP00000042903; -.
DR Ensembl; ENSORLT00000027078.1; ENSORLP00000042903.1; ENSORLG00000025701.1.
DR GeneTree; ENSGT00940000162888; -.
DR InParanoid; A0A3B3IFI5; -.
DR Proteomes; UP000001038; Chromosome 8.
DR Bgee; ENSORLG00000025701; Expressed in muscle tissue and 8 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR GO; GO:0032982; C:myosin filament; IBA:GO_Central.
DR GO; GO:0016460; C:myosin II complex; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000146; F:microfilament motor activity; IBA:GO_Central.
DR GO; GO:0006936; P:muscle contraction; IBA:GO_Central.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF44; MYOSIN-13; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 33..82
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 86..779
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 656..678
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1903..1944
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 843..1657
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1903..1929
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1944 AA; 222401 MW; 076E2929B11D8CF7 CRC64;
MSTDAEMEQY GPAAIYLRKP ERERIEAQTS PFDAKTAFFV VDADEMYLKC KLIKREGGKA
TVETEGGKTV TVKEDDIHPR NPPKFDKMED MAMMTHLNEP SVLFNLKERY ASWMIYTYSG
LFCVVVNPYK WLPVYDAQCV SGYRGKKRIE APPHIFSISD NAYQFMLTGD PEFSNIITKS
GAGKTVNTKR VIQYFATIAA LGGKKEQQSS GKIQGSLEDQ IVAANPLLEA YGNAKTVRND
NSSRFGKFIR IHFGSSGKLA SADIETYLLE KSRVTYQLSA ERSYHIFYQL MTGHKPELLE
ALLITTNPYD FPLISMGEIT VKSINDVEEF IATDTAIDIL GFNGEEKLGI YRLTGAVMHH
GNMKFKQKQR EEQAEPDGTE VADKIAYLMG LNSADMLKAL CYPRVKVGNE MVTKGQTVPQ
VNNSVSALCK SVYEKMFLWM VIRINEMLDT KQPRQFFIGV LDIAGFEIFD YNSLEQLCIN
YTNEKLQQFF NHTMFVLEQE EYKKEGIEWE FIDFGMDLAA CIELIEKPMG IFSILEEECM
FPKASDTTFK NKLYDQHLGK NKAFEKPKPG KGKAEAHFAM VHYAGTVDYN ITGWLDKNKD
PLNDSVVQLY QKSSNKLLCY LYAAHAGAED AGGAKKGGKK KGGSFQTVSA LFRENLAKLM
TNLKSTHPHF VRCLIPNESK TPGLMENFLV IHQLRCNGVL EGIRICTKGF PGRILYGDFK
QRYKVLNASV IPEGQFIDNK KASEKLLGSI DVDHSQYKFG HTKVFFKAGL LGTLEEMRDE
KLASLVTMTQ ALCRGYVMRK EFVKMMERRE SIYTIQYNVR SFMNVKNWPW LKLYFKIKPL
LQSAETEKEL QEMKGNYEKM KTDLAAALAK KKELEEKMVS LMQEKNDLQL QVASETENLS
DAEERCEGLI KSKIQLEAKL KETTERLEDE EEINAELTAK KRKLEDECSE LKKDIDDLEL
TLAKVEKEKH ATENKVKNLT EEMASQDESI AKLTKEKKAL QEAHQQTLDD LQAEEDKVNT
LTKAKTKLEQ QVDDLEGSLE QEKKLRMDLE RAKRKLEGDL KLAQESIMDL ENDKQQSDEK
IKKKDFEISQ LLSKIEDEQS LGAQLQKKIK ELQARIEELE EEIEAERAAR AKVEKQRADL
SRELEEISER LEEAGGATAA QIEMNKKREA EFQKLRRDLE ESTLQHEATA AALRKKQADS
VAELGEQIDN LQRVKQKLEK EKSEYKMEID DLSSNMEGVA KSKGNLEKMC RTLEDQLSEL
KAKNDENVRQ LNDLNAQRAR LQTENGEFSR QLEEKEALVS QLTRGKQAFT QQIEELKRLV
EEEVKAKNAL AHGVQSARHD CDLLREQFEE EQEAKAELQR GMSKANSEVA QWRTKYETDA
IQRTEELEES KKKLAQRLQE AEESIEAVNS KCASLEKTKQ RLQGEVEDLM IDVERANSLA
ANLDKKQRNF DKVLAEWKQK YEESQAELEG AQKEARSLST ELFKMKNSYE EALDQLETMK
RENKNLQQEI SDLTEQIGET GKSIHELEKA KKSVETEKSE IQTALEEAEG TLEHEEAKIL
RVQLELNQVK GEIDRKLAEK DEELEQIKRN SQRVIESMQS TLDAEVRSRN DALRVKKKME
GDLNEMEIQL SHANRQAAEA QKQLRNVQGQ LKDAQLHLDD ALRGQEDMKE QVAMVERRNG
LMLAEIEELR AALEQTERGR KVAEQELVDA SERVGLLHSQ NTSLLNTKKK LESDLVQVQG
EVDDAIQEAR NAEEKAKKAI TDAAMMAEEL KKEQDTSSHL ERMKKNLEVT VKDLQHRLDE
AENLAMKGGK KQLQKLESRV RELESEVESE QRRGADAIKG VRKYERRVKE LTYQTEEDKK
NVARLQDLVD KLQLKVKAYK RQAEEAEEMA NTHMSKLRKV QNEFEEAQER ADIAESQVNK
LRVKSRDAGK VNDNALCNTN PPKH
//
