ID A0A3B3IKS6_ORYLA Unreviewed; 539 AA.
AC A0A3B3IKS6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=LRRNT domain-containing protein {ECO:0000259|SMART:SM00013};
GN Name=lrrtm4l2 {ECO:0000313|Ensembl:ENSORLP00000044788.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000044788.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000044788.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000044788.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000044788.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000044788.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_011477756.1; XM_011479454.1.
DR AlphaFoldDB; A0A3B3IKS6; -.
DR STRING; 8090.ENSORLP00000044788; -.
DR Ensembl; ENSORLT00000042286.1; ENSORLP00000044788.1; ENSORLG00000030506.1.
DR GeneID; 101169042; -.
DR KEGG; ola:101169042; -.
DR CTD; 568695; -.
DR GeneTree; ENSGT00940000154909; -.
DR InParanoid; A0A3B3IKS6; -.
DR OrthoDB; 5344967at2759; -.
DR Proteomes; UP000001038; Chromosome 9.
DR Bgee; ENSORLG00000030506; Expressed in brain and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR24373:SF283; LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 4; 1.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF01462; LRRNT; 1.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 9.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..539
FT /note="LRRNT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017317177"
FT TRANSMEM 447..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..61
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT REGION 400..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 539 AA; 61781 MW; A53AD6FFF40094DE CRC64;
MGSVMLDWRL FCLLLHAAAL LLLSKGEKMC PASCRCERKI VYCESRNLLE IPVNISTGCQ
GLSLRNNNLM ALLPYQFAHL NQLVWLYLDH NSISSMDALA FHGVRRLKEL ILNSNEITHL
HNKTFSAIPN LRNLDLNHNQ LQSLQPGHFH GLRKLQNLHL RSNGLRQILI RTFLECRSLE
FLDLGYNHLR SLTRTTFLGL FRLRELHLEH NQFSKINFYV FPRLTNLRAL YLQWNRIRSV
SQGEPWIWQK LQKLDLSGNE IQMLDPAVFQ CMPNLQTLNL ETNKLSSVSA ETVAAWTSLT
TISLAGNAWD CSPSICPLMG WLRTFRDSKD ISMICSSPKS VQGEKVVDVV RNYSVCLFEE
LSTATIIILS TTQTEDVTTF PVQFGVTHLT HTVSPSKKFT LSPVRPTEAD RKTSESTTMT
FPSDISLETP TLFIPELQFE HMTFHKIIAG SVALFLSVSL ILLVIYVSWR RYPNTMRQLQ
QHSVNHKRRK KVHKQEQDLN SQLQEYYLSY HSNSEAMDSL VNETRPCTCT ISGSIECEV
//
