ID   A0A3B3Q3R3_9TELE        Unreviewed;       833 AA.
AC   A0A3B3Q3R3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Glutamate receptor 1-like {ECO:0000313|Ensembl:ENSPKIP00000000061.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000000061.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000000061.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B3Q3R3; -.
DR   Ensembl; ENSPKIT00000023944.1; ENSPKIP00000000061.1; ENSPKIG00000018816.1.
DR   GeneTree; ENSGT00940000157342; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022824; F:transmitter-gated monoatomic ion channel activity; IEA:UniProt.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:UniProt.
DR   CDD; cd13729; PBP2_iGluR_AMPA_GluR1; 1.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR019594; Glu/Gly-bd.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR001638; Solute-binding_3/MltF_N.
DR   PANTHER; PTHR18966:SF513; AMPA RECEPTOR SUBUNIT GLUR1B; 1.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR   Pfam; PF00497; SBP_bac_3; 1.
DR   SMART; SM00918; Lig_chan-Glu_bd; 1.
DR   SMART; SM00079; PBPe; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00023257};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Synapse {ECO:0000256|ARBA:ARBA00023018};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..833
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017353569"
FT   TRANSMEM        533..555
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        645..667
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          406..810
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00079"
FT   DOMAIN          416..481
FT                   /note="Ionotropic glutamate receptor L-glutamate and
FT                   glycine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00918"
FT   REGION          568..607
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          812..833
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        575..607
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   833 AA;  93577 MW;  32CEE0655781A9E2 CRC64;
     MQQSFAVLCI SFLGVCLGSS FPSNINIGGF FPSGSHEYEV FRFALLHHQD IPKLVPHVDM
     VNISDSFEMT YAFCSQFSKG VYAIIGLYDR RTVNMLMSFC GALHVCFITP SFPIEASNQF
     VIQLRPELQD ALVAIIEHYK WSKFVYMYSS HSGMTALQKV LDTAAEKNWM VTSINLLTMT
     EAAFLKVLQD LDKKKEGQII MDCELERLSS ILNLIAAQGR NLKSYHYILA NLGFLDIDLT
     EFKKSGANVT GFQLMNYSDP DVSRTIQEWL EFDSKDIKAP KKRLKYTGAL TYDGVSVMAA
     AFQNLRRQRI DISRRGNAGD CLANPPAPWG QGIDIQRALQ QVQIKGLTGH IQFNEKGRRT
     NYTVSVMELG ADGPKKVGYW NEEEKYVSTA TYTHGNNETF GLQNRTYIVT TILESPYVML
     KKNHDQFVGN DKYEGYCVEL AAEIAKHVGY TYKLEIVPDG KYGARDSETK MWNGMVGELV
     YGKADVAVAP LTITLVREEV IDFSKPFMSL GISIMIKKPT KSKPGVFSFL DPLAYEIWMC
     IVFAYIGVSV VLFLVSRFSP YEWQGGEMEE MDEHQSSQQQ QQQPPQSPAL ENQAQTPQNQ
     PLPQSQEHSN EFGIFNSLWF SLGAFMQQGC DISPRSLSGR IVGGVWWFFT LIIISSYTAN
     LAAFLTVERM VSPIESAEDL AKQTEIAYGT LDGGSTKEFF RRSKIAVFEK MWSYMKAADP
     SVFVKTTDEG VLRVRKSKGK YAYLLESTMN EYIEQRKPCD TMKVGGNLDS KGYGVATPKG
     SALRNPVNLA VLKLNEQGLL DKLKNKWWYD KGECGSGGGD SKNPRKPRGV EAQ
//