ID   A0A3B3Q4R8_9TELE        Unreviewed;       664 AA.
AC   A0A3B3Q4R8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Pleckstrin homology, MyTH4 and FERM domain containing H3 {ECO:0000313|Ensembl:ENSPKIP00000000645.1};
GN   Name=PLEKHH3 {ECO:0000313|Ensembl:ENSPKIP00000000645.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000000645.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000000645.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B3Q4R8; -.
DR   STRING; 1676925.ENSPKIP00000000645; -.
DR   Ensembl; ENSPKIT00000024543.1; ENSPKIP00000000645.1; ENSPKIG00000019216.1.
DR   GeneTree; ENSGT00940000159764; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR000857; MyTH4_dom.
DR   InterPro; IPR038185; MyTH4_dom_sf.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR46049; AGAP003327-PA; 1.
DR   PANTHER; PTHR46049:SF5; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF00784; MyTH4; 1.
DR   Pfam; PF00788; RA; 1.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM00139; MyTH4; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50057; FERM_3; 1.
DR   PROSITE; PS51016; MYTH4; 1.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          155..311
FT                   /note="MyTH4"
FT                   /evidence="ECO:0000259|PROSITE:PS51016"
FT   DOMAIN          316..664
FT                   /note="FERM"
FT                   /evidence="ECO:0000259|PROSITE:PS50057"
SQ   SEQUENCE   664 AA;  75267 MW;  62B27940B47A5CDE CRC64;
     MPFPGFCWLL CCRQGFSLLG RDYGEKEEEE SFELRSKDEL ACSVRRSDVQ EEMLSLIIEK
     CKMGLENDPE QVVKWLYREA PGSWIRQRRH WFVLTHDSLD CYSSSEKGAR RLGTLVLTSL
     CSVAWPDKQT YKETENRFNL EVVEHIYKHN PILSYTQSPL YAPLLPFPYG SSDHVGKGYG
     TVREEAVRLF NCLQQLETAA EAVPLIQGVL QTCLDLRPLR DEVYCQLVKQ TSGAACACVP
     RQLRYWQLLT CMSCTFLPGP AVLKYLRFHL KVRNQNPNTE MDNYASFIWE ALQKTRCREC
     VPSWEEIQVL MARREILCLV HYPGPGSCRV PITSHTTADE LVKMVSEKLG MQDSRNTFAL
     FEQNAHQERA VSGSTIIADI LTRFEKDPDP ESQWRLSFKL YCLLDADSIS VDSIEYIFLF
     EQCHEMMVRG QLPASEEDLQ DLAALRLQCL MGDFSTHSPC PPLDEVFPGN VVEARVLLAL
     KPPPGTPSTG PNLPMGCPQR FAGGFLAGAL WSHTAAHKQR VEQDLRLHGR LKEEGAAVMG
     AIVERWKGLA GYSRRESIAA YLTIARQWSG FGCTLYEVDF YISSTGSFSQ KLWLGVAAKC
     ISLYRQGEAE ALESFPYGQI CSYGVFDSNT FKITAGDRDL LFETSKLTEI MQLMNAYLSA
     AQRY
//