ID A0A3B3Q5F5_9TELE Unreviewed; 388 AA.
AC A0A3B3Q5F5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Platelet-derived growth factor (PDGF) family profile domain-containing protein {ECO:0000259|PROSITE:PS50278};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000001084.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000001084.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family.
CC {ECO:0000256|RuleBase:RU003818}.
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DR AlphaFoldDB; A0A3B3Q5F5; -.
DR STRING; 1676925.ENSPKIP00000001084; -.
DR Ensembl; ENSPKIT00000024995.1; ENSPKIP00000001084.1; ENSPKIG00000019503.1.
DR GeneTree; ENSGT00940000156167; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0005172; F:vascular endothelial growth factor receptor binding; IEA:UniProt.
DR CDD; cd00135; PDGF; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR004153; CXCXC_repeat.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR023581; PD_growth_factor_CS.
DR InterPro; IPR000072; PDGF/VEGF_dom.
DR PANTHER; PTHR12025; VASCULAR ENDOTHELIAL GROWTH FACTOR; 1.
DR PANTHER; PTHR12025:SF3; VASCULAR ENDOTHELIAL GROWTH FACTOR C; 1.
DR Pfam; PF03128; CXCXC; 2.
DR Pfam; PF00341; PDGF; 1.
DR SMART; SM00141; PDGF; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00249; PDGF_1; 1.
DR PROSITE; PS50278; PDGF_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|RuleBase:RU003818};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..388
FT /note="Platelet-derived growth factor (PDGF) family profile
FT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017286473"
FT DOMAIN 82..183
FT /note="Platelet-derived growth factor (PDGF) family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50278"
SQ SEQUENCE 388 AA; 43282 MW; 10AADD0A38E34427 CRC64;
MWMLSLALWI LGVSNLTHGS HADEPTFEPP QASSLDELLE MLYPEYSLVQ DCLRRRMHGA
PWRSHTATDD MWGDPREMAL YKFDGTFEVI MQEIQRTVCR PREVCLEVSK ENPESTSNFY
LPRCVSVHRC GGCCNHEALY CGNTSHSLIN KTLVELSPPR MERSVIMVTF VNHTACECQG
KRPLHSIIRR AAVSHRPLCS EPDVPCDPGW EWNAAGCQCV PAGTHPSPAP VPDPLDAALL
ALCGPNKVLD EGRCECVCEN GLTEASCGAG WRLDAAACEC VCDGLPAPGT CPPSQRWEPE
LCGCICRATC PRSQPLNPDT CLCQCRESER SCLLQGKKFN RDNCSCYRLP CRTPRRKCPP
GHYYSPSVCQ CVPNYMRSGE WNWGGRRD
//
