ID A0A3B3Q643_9TELE Unreviewed; 433 AA.
AC A0A3B3Q643;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=ADAM metallopeptidase with thrombospondin type 1 motif, 15b {ECO:0000313|Ensembl:ENSPKIP00000001628.1};
GN Name=ADAMTS8 {ECO:0000313|Ensembl:ENSPKIP00000001628.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000001628.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000001628.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3Q643; -.
DR STRING; 1676925.ENSPKIP00000001628; -.
DR Ensembl; ENSPKIT00000025554.1; ENSPKIP00000001628.1; ENSPKIG00000019854.1.
DR GeneTree; ENSGT00940000159642; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0062023; C:collagen-containing extracellular matrix; IEA:InterPro.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 3.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR013277; Pept_M12B_ADAM-TS8.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723:SF41; A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 8; 1.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 2.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01861; ADAMTS8.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR PRINTS; PR01705; TSP1REPEAT.
DR SMART; SM00209; TSP1; 3.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 3.
DR PROSITE; PS50092; TSP1; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 103..170
FT /note="ADAMTS/ADAMTS-like cysteine-rich"
FT /evidence="ECO:0000259|Pfam:PF19236"
FT DOMAIN 177..290
FT /note="ADAMTS/ADAMTS-like Spacer 1"
FT /evidence="ECO:0000259|Pfam:PF05986"
FT DISULFID 18..55
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 22..60
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 33..45
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
SQ SEQUENCE 433 AA; 46924 MW; 92FDBA0EE13C2A35 CRC64;
MQVAVDGSWG AWSPWGRCSR TCGGGVEFSH RQCTSPEPQN GGRYCEGQRV KYRSCQTGAC
GGDGGKSFRE EQCEKYNSFS YLDIHGNVKE WIPKYAGVSP RDRCKLFCRA KGSSEFKVFE
AKVVDGTTCG PDTTSICVQG QCVKAGCDQE IGSNAKLDKC GVCAGNGSSC RRVAGALSKA
VYGYSDIVTI PAGATNIDVK QRSHRGVKHD GHYLAIQAED GSYILNGNFS VSMVEQDIPV
AGAVLRYSGS STTLERIQSF QRLREAITIQ LLATAGEASP PKVKYTFFLP KDVPFSKAKE
KKGSPHVIQP LGVPQWSLGE WSECSKTCGS GWSRRDVECR DTGGFLSELC DQDLRPADIR
ACADLPCPVW QMGPWSSCSR TCGLGVRRRS VFCTDYTGKT VDPERCDPAR LPEPVSGECL
TQECEGLAVQ GGQ
//
