ID A0A3B3QE18_9TELE Unreviewed; 623 AA.
AC A0A3B3QE18;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=FERM domain containing 3 {ECO:0000313|Ensembl:ENSPKIP00000004393.1};
GN Name=FRMD3 {ECO:0000313|Ensembl:ENSPKIP00000004393.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000004393.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000004393.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3QE18; -.
DR Ensembl; ENSPKIT00000028375.1; ENSPKIP00000004393.1; ENSPKIG00000021510.1.
DR GeneTree; ENSGT00940000158577; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd17102; FERM_F1_FRMD3; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF8; FERM DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 555..577
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..305
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 509..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..536
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 70854 MW; C3668D099C3B7752 CRC64;
MSTGITNNHR INFLTVEIPC LRCISPLRTC IKERNMKVTQ MERDTKGQFL LDHVCNHYSL
LEKDYFGIRY VDLQKQRHWL EPNKTITKQM KAQPPYTMCF RVKFYPYEPM KIKEELTRYL
LYLQLKRDIY HGRLLCPFAD AAYLGACIVQ AELGDYDPDE HPADYISDFQ LFPKQSQKLE
RKIMEIHRNE TRGQCPAVAE MNLLQRAHTL ETYGVDPHPC KDFTGSTAFL GFTATGFVVF
QGNKRIHLLK WADVSKLKFE GKTFYVIGLQ KEKKLVLTFH TSTPAACKHL WKCGVENQAF
YKCAKSSQIK TVSSSNIFFK GSRFRYSGKV AKEVIEASSK IQRDPPEVHR SSFSQSRSFN
SLSNRQLIMN MEPLLPALPS PSESEEPCME PAVKRRPRTQ MQFGKAKGLL ALKESVHLSP
LKLAIVSQPE AGKDGAEWGA GDVPPSEERM LCKEERRHEE DEEEGCDALT ISELVYNPCA
SLLPTPVEDV GGVDLLFESP VKLLKELHAD SGLRDEPEGE QECEGAQEER ARDAPRGLSP
RAGGSAPLGA CLRSLARLLA LALGLLMILL PLLLLLLESD IDVSFLREIR QTPEFEQFHY
EYYCPLRRWV VCKINIVLDK LGG
//
