ID A0A3B3QF26_9TELE Unreviewed; 523 AA.
AC A0A3B3QF26;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Large neutral amino acids transporter small subunit 1-like {ECO:0000313|Ensembl:ENSPKIP00000004728.1};
GN Name=SLC7A5 {ECO:0000313|Ensembl:ENSPKIP00000004728.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000004728.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000004728.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
CC {ECO:0000256|ARBA:ARBA00007040}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B3QF26; -.
DR Ensembl; ENSPKIT00000028715.1; ENSPKIP00000004728.1; ENSPKIG00000021715.1.
DR GeneTree; ENSGT00940000155581; -.
DR OrthoDB; 1103451at2759; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015804; P:neutral amino acid transport; IEA:UniProt.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR004760; L_AA_transporter.
DR NCBIfam; TIGR00911; 2A0308; 1.
DR PANTHER; PTHR11785; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR11785:SF315; LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 1; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 66..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 523 AA; 57277 MW; 1B320BB624E8776D CRC64;
MSKLKKRSNH LSPDRAEEEK GALEKTLPSE RHENGHAIQP SVTEEGKPST ESGNIPEDTV
VLKRTITLVN GVAIIVGTII GSGIFLTPTE VVKEAGSAGM SLIIWTACGL FSMVGALCYA
ELGTTISKSG GDYAYILEVY GPFPAFLKLW IELLIIRPSS QYIIAYTFAT YLLKPLFPGC
PVPEQAAKLI ACLCVLLLTA VNCCSVKATT KVQNIFTASK LLALSVVIIL GLIQIAKGEA
QGLSLQKSFE GTNWDVGDIG LALYSGLFAY GGWNYLNLVT EEMIEPYKNL PRAIMISLPL
VTIVYVLTNL AYFTTLTPEE MLQSEAVAVD FGNWHLGPMA WMIPVFVGLS CFGSVNGSLF
TSSRLFFVGA REGHLPSLLS MIQPSLLTPV PSLIFTCVMT LLYAFSNDIS SVINFFSFFN
WVCIAMAIIG MMWLRYRKPN LDRPIKVNLL LPVSFVLACL FLIVVSFWKT PAECGLGVIV
MSTGIPFYYF GVAWSNKPKW LQQAIFSSTV FAQKLLDVVP QDL
//
