ID   A0A3B3QH33_9TELE        Unreviewed;      1162 AA.
AC   A0A3B3QH33;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Unc-13 homolog C {ECO:0000313|Ensembl:ENSPKIP00000004716.1};
GN   Name=UNC13C {ECO:0000313|Ensembl:ENSPKIP00000004716.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000004716.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000004716.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3QH33; -.
DR   STRING; 1676925.ENSPKIP00000004716; -.
DR   Ensembl; ENSPKIT00000028703.1; ENSPKIP00000004716.1; ENSPKIG00000021669.1.
DR   GeneTree; ENSGT00940000155174; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0098793; C:presynapse; IEA:UniProt.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0019992; F:diacylglycerol binding; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0048468; P:cell development; IEA:UniProt.
DR   GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   CDD; cd04027; C2B_Munc13; 1.
DR   Gene3D; 1.10.357.50; -; 1.
DR   Gene3D; 1.20.58.1100; -; 1.
DR   Gene3D; 3.30.60.20; -; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 2.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR010439; MUN_dom.
DR   InterPro; IPR014770; Munc13_1.
DR   InterPro; IPR014772; Munc13_dom-2.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR027080; Unc-13.
DR   InterPro; IPR037302; Unc-13_C2B.
DR   PANTHER; PTHR10480; PROTEIN UNC-13 HOMOLOG; 1.
DR   PANTHER; PTHR10480:SF2; PROTEIN UNC-13 HOMOLOG C; 1.
DR   Pfam; PF00130; C1_1; 1.
DR   Pfam; PF00168; C2; 2.
DR   Pfam; PF06292; MUN; 1.
DR   PRINTS; PR00360; C2DOMAIN.
DR   SMART; SM00109; C1; 1.
DR   SMART; SM00239; C2; 2.
DR   SMART; SM01145; DUF1041; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR   PROSITE; PS50004; C2; 2.
DR   PROSITE; PS51258; MHD1; 1.
DR   PROSITE; PS51259; MHD2; 1.
DR   PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          44..94
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   DOMAIN          150..274
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          579..722
FT                   /note="MHD1"
FT                   /evidence="ECO:0000259|PROSITE:PS51258"
FT   DOMAIN          826..969
FT                   /note="MHD2"
FT                   /evidence="ECO:0000259|PROSITE:PS51259"
FT   DOMAIN          990..1117
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
SQ   SEQUENCE   1162 AA;  132228 MW;  5C8D5C46BAE3D26B CRC64;
     LAARKAGVSF ALVARSTLNN EDLKLHVLRK TLQALIYPIS STTPHNFEVW TATAPTYCHE
     CEGLLWGIAR QGVRCSECGV KCHEKCQDLL NADCLQRAVE KSSKHGAEDK TQNIIMAMKE
     RMKIRERNRP EVFQLIQEVF QISKEDFTTH LKAAKQAVLE GTSKWSAKIT ITVLCAQGLQ
     AKDKTGSSDP YVTVQVGKTK RRTKTIFGNL NPIWDEKFFF ECHNATDRIK VRVWDEDDDI
     ASRVKQHFKK ESDDFLGQTI IEVRTLSGEM DVWYNLEKRT DKSAVSGAIR LKISVEMKGE
     EKAAPPHGQY TCLHENLFHC LTEVKNNGVV KIPEVKGEEA WKVYFDDTAQ EIVDEFAMRF
     GVESIYQAMT HFSCLSSKYM CPGVPAVMSN LLANINAYFA HTTTATTNIS ASDRFAASNF
     GREKFIKLLD QLHNSLRIDL SKYRDNFPAS NPERLQDLKS TVDLLTSITF FRMKVQELQS
     PPRASMVVKD CVRACLDSTY KYIFDNCHEV YNQLLDQDMP REEQGPSIKN LDFWPKLITL
     MVSVIDEDRT AYTPVLNQFP QELNMGKVSA EITWNLFATD MKYAMEEHEK HRLCKSTEYM
     NLHFKVKWFH NEYVRDLAAF KDTIPEYSLW FEPFVIQWLD ENEDVSMDFL NGALERDKKD
     GFQQTSDHAL FSCSVVDVFA QLNQSFEIIR KLECPNPQAL GHFMCRFAKT INKVLLEYAA
     IISKDFSSHL SREKVPCILL NNIQQLRVQL EKMFEAMGGK QLDAEAGDLL KELQNKLNTV
     LDELSGVFGS SFKPVIEDCV KQMSQELLQM KGDGAAKKSS AAMDAEIVLR PLMELLDKNL
     MLFAKICEKT VLKRVLKELW KIVLNTIERQ VVLPPLTDQS QGAQMIFNAA KDLGQLSKLK
     EHVIREEARS LTPRQCAAMD LVLPTIKQYF HAGGNGLKKS FLEKSPDLKS LKYALSLYTQ
     STDALIKKYI GTQNSQGEII RFMFQPSNGS LGEVSLQVDL VSHPGTGEHK ISVKVAAVKS
     ISWQTNAMFR PFVEVNAVGP QLADKKRKFS TKTKNNTWSP KYNETFQFVL SSEHEPQAYE
     LHVSVKDYCF AREDRIIGMT VIPLKDLADK GSCSGWHPLV RDISMNETGL IIMRILSQRT
     NDEVAKEFVR LKSDVRSAEE TL
//