ID   A0A3B3QJN9_9TELE        Unreviewed;       766 AA.
AC   A0A3B3QJN9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=NACHT domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000006328.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000006328.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3QJN9; -.
DR   Ensembl; ENSPKIT00000030351.1; ENSPKIP00000006328.1; ENSPKIG00000022657.1.
DR   GeneTree; ENSGT01100000263547; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd08321; Pyrin_ASC-like; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR004020; DAPIN.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF02758; PYRIN; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 2.
DR   SMART; SM01289; PYRIN; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50824; DAPIN; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          1..96
FT                   /note="Pyrin"
FT                   /evidence="ECO:0000259|PROSITE:PS50824"
FT   DOMAIN          193..326
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   766 AA;  87823 MW;  10E8ECF809E5B13F CRC64;
     MAHQETQTSL PNLLLEYLEE LDGEQLKKFK WKLSHTKYKE LKPLPKGQVK DLDKTDLADT
     MISYYMEVGA LEVTIEILKK MTLNDLAKRL CNRVRSELGD ILEKRELMLD RIKCNLKNKF
     EFVTEGKAKE GESTLLKEIY TELYITKGGP GGVNDEHEVR QIETAPKKRR TEDTTVKCND
     IFKPLCGLET PIRTVLTKGV AGIGKTVSVH KFILDWAEGK ANQDIHFIFA LPFRNLNLLK
     GEFSLIELLH HFDPELKLFQ STELFRCKIL FIFDGLDECR LPLDFQNNVS WFDVMKKTSL
     DVLLTNLIMG NLLPSALFWI TSRPAATNQI PPECIHQVTE IRGFSDAQKE EYFRRRFSDE
     SLASRIITHV KSSRSLFIMC HIPVFCWISA TVLESLFCET DSGEIPRTLT EMYTHFLIFQ
     ASLKNDKYRL QTSATQNRRS WYRKLKDGWM KKNETKIIKC FLIKLGKLAF HNLEKGNLIF
     YEKDLEQSDL DVRETSVYSG VCTEVFKKEY GLYREKVYCF VHLSIQEYLA ALYVVLSKSS
     ASLLKTAVKQ ALNSKNGHLD LYLRFLLGLS TDSSKTLLER LLGQTRLSSH NIGKTAQYIK
     GKIKENLSPE RTINLFHCLN ELGDNSLVEE GQRYLNSGRL SAEDLSPAQY SALAFVLLMS
     EEELDVFDLK KFFRSDNEHW RLLPVVKTSK TALLNSCNLT EKCCDALASA LRSNSSPLRE
     LDLSNNELQD SGVKLLSAGL GDSHCKLEIL RLSGCRVTER RFCDIM
//