ID   A0A3B3QK59_9TELE        Unreviewed;       616 AA.
AC   A0A3B3QK59;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3) {ECO:0000313|Ensembl:ENSPKIP00000005801.1};
GN   Name=MPP3 {ECO:0000313|Ensembl:ENSPKIP00000005801.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000005801.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000005801.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MAGUK family.
CC       {ECO:0000256|ARBA:ARBA00007014}.
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DR   AlphaFoldDB; A0A3B3QK59; -.
DR   STRING; 1676925.ENSPKIP00000005801; -.
DR   Ensembl; ENSPKIT00000029814.1; ENSPKIP00000005801.1; ENSPKIG00000022310.1.
DR   GeneTree; ENSGT00940000157190; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00071; GMPK; 1.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 1.10.287.650; L27 domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR008145; GK/Ca_channel_bsu.
DR   InterPro; IPR008144; Guanylate_kin-like_dom.
DR   InterPro; IPR020590; Guanylate_kinase_CS.
DR   InterPro; IPR014775; L27_C.
DR   InterPro; IPR004172; L27_dom.
DR   InterPro; IPR036892; L27_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR23122:SF33; MAGUK P55 SUBFAMILY MEMBER 3; 1.
DR   PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR   Pfam; PF00625; Guanylate_kin; 1.
DR   Pfam; PF02828; L27; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   Pfam; PF07653; SH3_2; 1.
DR   SMART; SM00072; GuKc; 1.
DR   SMART; SM00569; L27; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF101288; L27 domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR   PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR   PROSITE; PS51022; L27; 1.
DR   PROSITE; PS50106; PDZ; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          115..172
FT                   /note="L27"
FT                   /evidence="ECO:0000259|PROSITE:PS51022"
FT   DOMAIN          191..272
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          280..350
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          413..600
FT                   /note="Guanylate kinase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50052"
FT   REGION          13..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          359..395
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   616 AA;  69228 MW;  D78DD0C9B88C2FF2 CRC64;
     MCVRLSASFR ATRNVGPSDL PAASRRQPQG GHGLPEGRLQ REEPGIPDEG TYVSAVFPPT
     QKHKQSRQTQ LIYPSAMRLG VRVGGGSLHE DLTPSPPPVS AQIHERLRLY ECQCPAPVLH
     SASSLVEDVA EELQGKSMSS NEKELLRLLM SPHFKAVLFA HDTVAQKNFD PVLPPLPDDL
     EDELEEATVK IVRLVKNKEP LGATIRRDET TGAVVVARIM RGGAADRSGL VHVGDELREV
     NGICIAHKRP DEISHLLSQS QGSITLKIIP AVKEEDRLKE SKVYMKALFD YNPSEDKATP
     CQEAGLPFKR GDILQVVSHD DPTWWQAKRV GDSNLRAGLI PSKSFQERRL AYRVKMGTMP
     HLRSPGRPLS GLRRSFRLSR KGRQDTPEET PPESEFLTYE EVTRYQQRPG ERPRLVVMIG
     SLGARINELK QRVIAENPHR YGVAVPHTTR PKKTHEKDGV EYHFVSKQAF DADAQNNKFI
     EYGEYKENLY GTSLEAIRSV QAKNKLCIAD VQPEALKTLR TAEFKPYVIF VKPRIPESQP
     RHTSGTSPAG GEQYRITDED LEEMRQSGAQ MDQQYGHWVD RVLVKEDMAS ACAELRGILE
     RLEREPSWVP VSWLRT
//