ID A0A3B3QLY4_9TELE Unreviewed; 2037 AA.
AC A0A3B3QLY4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Fras1 related extracellular matrix 1a {ECO:0000313|Ensembl:ENSPKIP00000007123.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000007123.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000007123.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FRAS1 family.
CC {ECO:0000256|ARBA:ARBA00005529}.
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DR STRING; 1676925.ENSPKIP00000007123; -.
DR Ensembl; ENSPKIT00000031167.1; ENSPKIP00000007123.1; ENSPKIG00000023122.1.
DR GeneTree; ENSGT00940000156990; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd00037; CLECT; 1.
DR Gene3D; 2.60.40.2030; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR039005; CSPG_rpt.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045658; FRAS1-rel_N.
DR PANTHER; PTHR45739:SF7; FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1; 1.
DR PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF16184; Cadherin_3; 12.
DR Pfam; PF03160; Calx-beta; 1.
DR Pfam; PF19309; Frem_N; 1.
DR Pfam; PF00059; Lectin_C; 1.
DR SMART; SM00237; Calx_beta; 1.
DR SMART; SM00034; CLECT; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF141072; CalX-like; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
DR PROSITE; PS50268; CADHERIN_2; 1.
DR PROSITE; PS51854; CSPG; 12.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|PROSITE-ProRule:PRU00043};
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT REPEAT 296..390
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 413..500
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 521..615
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 642..753
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 775..866
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 887..981
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1026..1128
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1149..1239
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT DOMAIN 1152..1263
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REPEAT 1260..1357
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1378..1470
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1491..1581
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1615..1709
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT DOMAIN 1916..2025
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT REGION 1840..1863
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1842..1863
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2037 AA; 228455 MW; AE19B9211E0804E2 CRC64;
LISTFSRCVF LSGMADRGRD SLVTVNRGLK VKRGQTAYLE EEDLRFSAPQ DRDACKVEVV
LNEPITQRVG VLTPQVFDCY FHADEVKYVH NGCPILKEDK VMLRLFRFTE TETYTEVFFL
RVEVLEPDCS IIHLGPKSLE VPEFYSLSDK LDGNAVSFHY ERRSNLECTV QVATQEAHLP
AHGQLVTGEP EEVVPRGDEP QSFLPSEQQL INKARAMCKE SACLNGMKLV QFIKVPCEEF
LVMGLKYQHT DPPSPDIDYI AIRLDLRDTR SRSIYKSERA WIPVRIKNGI PNQPPKPAFM
PTFILEVDQF ILTPFSTAAV DAEDAESPRS LLVFNITKPP QEGFITHLSD HTKPIISFTW
ADLHDMLIAY QPPNSSHTQR RNYEVEFDVH DYFFAKSAPF MVHVSVRTAD TNAPRVSWNM
GLSLLEGQSR PITWEQLQIV DNDNLKLVRI ITVDGLQHGR LTVRGGKGFM FTVSDIQAGV
VRYHHDDSDT TKDFVVFRIT DGHHQTRHKF PINILPKDDS PPFLITNMVL ELAEGQIALL
QGSVLQASDM DSSDDYILFN VTRPPQAGVL MKIPGPRETG YPVSHFLQRD LFHSVIYYRH
LGNEIFDDSF EVVLSDFHDP PNLSEHQVIV VHITPVHDQL PKEVPGVTRH IVVKEMEVVH
ITKKQLHFVD PESPDSELTY TITTPPFFSS IHGGDAGRLF LVDSIPKFTK DPSAPVLRLF
TQHAVNYMKV AYMPPLQEIG IHPQPIQFVL SVTNQQGSTL IGICFNVTVL PVDNQPPQVH
MNPLTVEEGG ECPMDSDHLW LTDPDTAEEA LRVELRAGPQ HGRLHLDGFP VDPGQAFALS
DLTSLKVRYH HDGSETVQDS IYLTASDGIN VAEFVLQVEV ALVNDEVPVL APGLRLVLDC
AEGQEVVITT EYLYATDRDT NDSRLSYMIA RQPYHGVVRK NGVVVDRFIQ ADLISGFITY
KHTGAEIGFT PRYDIITFVI SDEEAENFPA CTSDGQPSPL SPAARLQKAL PIYDMNVTVF
PVDNQAPSLI TGEVFVVDEG ASASITVAHL RVSDVDTPLE ELEFILVSPP QFGYIENILP
SPGFEKSNMG ISIATFTYGD VKNGHVNYVQ SRHQRTEPTA DQFMVRVSDG IRQSSDTPFY
IIIRPTNDEV PDFLTRNITV SEGHSKGLDP TILDAVDLDV PRDRLSFSII EQPLHGALTA
NTGTAMHDFT MDELRNGMTI TYAHDDSETT VDGFTIQLTD GKHQLRKRVE VTVLPINDEL
PHIIRNTGIE VDMGESRLIS GVVLAAWDDD TPARDVLYVF ESLPTEGLLQ MKMGLHWVSL
SAGENCSQED LDSNLLRYLH TGSTGLQRED AFIFHLQDGA NRSPVQHFRI SVKTMEKGDI
AVFVKPVQAR RGERVVLTTE VLLALDGTDR PEELLYVVTT PPDHGHVEYI HHPGMAITSF
SQMDVAANLV CYIHDNSAVS PQETLRFVVS NGQSTRGGVL DIAIDTVDRE LPSILHNSGL
QVPQGTTMVL SPDVLSLSDP DTPPSRLFFV LVQPPQYGQL LLRGAPFLEG NFTQQNLLDL
QLAYRHGGGP AQIDRFSFTA LDSSHRGFLM GGKLQTEPVF FTIQVEPLGI PAPRLVHLKV
AWRAEVLKDG RYGIFVSSRE LKAQGTDCHS EQLVFQVLRP PHFGYLENVT SGEFIRQRFT
QRDLNRRNIL YVINPASSAL SDSLEFKVSD PLGNANPTHT FEFRWASLEL SQAEYRVCEE
EDLLLLTVLR SGNTAESSYV TIKVKEITAS RGKDFTLSPS SLLQFDPGVT SRTWRLEITQ
DQLEEEDETF EVSLASPEGA VLGCNTSALV TIIDSGIGEN PPTSPHLVSQ HSGSPSRQDV
PQYHSPRTCT MELTGLLHFN QSSNALWRCD GAAWRPWTPS HQAIDAQKCP QGWTYHSARC
YILSKGPRLT WALAARTCKE AYNGSLVSVL SEQDMDWLWD FSGRKPFWIG LNDRENREHW
EWVGGEPVTY TNWKRNPLRT KRKGNVRRCA LVLRRARWHT RDCSKGKGHH YVCYTQT
//
