ID   A0A3B3QNW8_9TELE        Unreviewed;       528 AA.
AC   A0A3B3QNW8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Transmembrane protein 181 {ECO:0000313|Ensembl:ENSPKIP00000008402.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000008402.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000008402.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B3QNW8; -.
DR   STRING; 1676925.ENSPKIP00000008402; -.
DR   Ensembl; ENSPKIT00000032482.1; ENSPKIP00000008402.1; ENSPKIG00000023911.1.
DR   GeneTree; ENSGT00390000007183; -.
DR   OrthoDB; 5478455at2759; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015643; F:toxic substance binding; IEA:InterPro.
DR   InterPro; IPR040416; TMEM181.
DR   InterPro; IPR047843; WLS-like_TM.
DR   PANTHER; PTHR31918; TRANSMEMBRANE PROTEIN 181; 1.
DR   PANTHER; PTHR31918:SF1; TRANSMEMBRANE PROTEIN 181; 1.
DR   Pfam; PF06664; MIG-14_Wnt-bd; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        61..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        228..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        266..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        371..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        407..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        449..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          176..474
FT                   /note="Wntless-like transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF06664"
SQ   SEQUENCE   528 AA;  61300 MW;  62F24175C848E51F CRC64;
     MDRMDSDYAS FENPLFRDLK YFCKKIQEAY EELKEDLTPY RDDRFYRLAP MRLYTLSKRH
     FVLVFVVFFI CFGLTVFVGI AGPKIIEEYS ATNSSHTKTG PFSLQSLPLS TYNQQLWLTC
     QIQLEHPSGV DYSQPLEINV ELKGVMQDAS VTRISSNVHQ KSRILHCGAV NVHPPTCDEI
     IVVHLGYLNY TRYHVNVSFK GLENLTFGIR EVTFMWKTYN PSFSQVEIWF RFVFVVLTFV
     VTCMFAHSLR KFSMRDWGIE QKWMSILLPL LLLYNDPFFP LSFLVNSWFP GTLDALFQAV
     FLCALLLFWL CVYHGIRVQG ERKCMTFYLP KLVIVGLIWL SSITLGIWQT VNELHDPTYQ
     YKVDIGNFQG MKIIFLVVVS VYILYLIFLI VRACSELKNM PYTDLRLKFL TALTFIVLII
     SMVILYLRFG AKVLQDNFVA ALSTHYKNSA EFLSFYGLLN FYLYTLAFVY SPSKSALYDS
     QLKDNPAFSM LNDSDDEVIY GSDYEEMPLQ NGRAIKATSK YQDETDSD
//