ID A0A3B3QQU6_9TELE Unreviewed; 647 AA.
AC A0A3B3QQU6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Rabphilin-3A-like {ECO:0000313|Ensembl:ENSPKIP00000007781.1};
GN Name=RPH3A {ECO:0000313|Ensembl:ENSPKIP00000007781.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000007781.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000007781.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 1676925.ENSPKIP00000007805; -.
DR Ensembl; ENSPKIT00000031849.1; ENSPKIP00000007781.1; ENSPKIG00000023544.1.
DR Ensembl; ENSPKIT00000031873.1; ENSPKIP00000007805.1; ENSPKIG00000023544.1.
DR Ensembl; ENSPKIT00000031897.1; ENSPKIP00000007829.1; ENSPKIG00000023544.1.
DR GeneTree; ENSGT00940000157468; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd04035; C2A_Rabphilin_Doc2; 1.
DR CDD; cd08384; C2B_Rabphilin_Doc2; 1.
DR CDD; cd15762; FYVE_RP3A; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR041282; FYVE_2.
DR InterPro; IPR028698; FYVE_RPH3A.
DR InterPro; IPR010911; Rab_BD.
DR InterPro; IPR043566; Rabphilin/DOC2/Noc2.
DR InterPro; IPR047022; Rabphilin_Doc2_C2A.
DR InterPro; IPR001565; Synaptotagmin.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45729; RABPHILIN, ISOFORM A; 1.
DR PANTHER; PTHR45729:SF3; RABPHILIN-3A; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF02318; FYVE_2; 1.
DR PRINTS; PR00360; C2DOMAIN.
DR PRINTS; PR00399; SYNAPTOTAGMN.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS50916; RABBD; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 38..154
FT /note="RabBD"
FT /evidence="ECO:0000259|PROSITE:PS50916"
FT DOMAIN 86..142
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 345..467
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 503..636
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 647 AA; 72118 MW; 40DFDE8EB14609E9 CRC64;
MTDAVMGTSS ERWGPHGRQS RMPASDKDQA DWTPQPNPPP GDDLTDEEKE IINGVIARAE
KMEAMEQERI GRLVNQLDTI KKTVCGDGVS RCLLCGELLG APGVSSVVCE DCKKNMCTKC
GIQTGRRPRA VWLCKICGEQ REVWKRSGAW FFKGMPKQML PSPIPISKNR EASAQPIPSA
QEPPGPEARA PSQPRTQSRG PVESQSHSSE QQLTETQPSG RGGYPPVPPK PTDVQPGRGL
YRGESSDDTQ GSPVVLKRAV PVQSSRPPQT QAASAKAEQA PMEMEPNYSS APAPLREERV
PSGVQEERRQ PAAAYSRAPV RHQPPPPEKD EEEEANSYDS DEATTLGSLE FTLLYEQENN
SLHCNIMKAK GLKPMDSNGL ADPYVKLHLL PGASKSTKLR TKTLRNTRNP TWNETLVYHG
LTDEDMQRKT LRISVCDEDK FGHNEFIGET RVALKKMKMN QKKNFNVCLE RVVPVKRTAT
GGGARGISLY EDETGKDIGD VEERGRILIS LMYNTQQNRL IVGVVRCVHL AAMDANGYSD
PFVKICLKPD MGKKAKNKTQ IKKKTLNPEF NEEFSYDIKH SELAKKTLDI SVWDYDIGKC
NDYIGGCQLG ITAKGERLKH WYECLKNKDK KIERWHTLMN ENHVSSD
//
