ID   A0A3B3QUJ2_9TELE        Unreviewed;      1114 AA.
AC   A0A3B3QUJ2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=AF4/FMR2 family member 4-like {ECO:0000313|Ensembl:ENSPKIP00000009081.1};
GN   Name=AFF4 {ECO:0000313|Ensembl:ENSPKIP00000009081.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000009081.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000009081.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the AF4 family. {ECO:0000256|ARBA:ARBA00007354}.
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DR   Ensembl; ENSPKIT00000033178.1; ENSPKIP00000009081.1; ENSPKIG00000024325.1.
DR   Ensembl; ENSPKIT00000033196.1; ENSPKIP00000009099.1; ENSPKIG00000024325.1.
DR   GeneTree; ENSGT00950000182974; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR   Gene3D; 6.10.250.2670; -; 1.
DR   InterPro; IPR007797; AF4/FMR2.
DR   InterPro; IPR043640; AF4/FMR2_CHD.
DR   InterPro; IPR043639; AF4_int.
DR   PANTHER; PTHR10528; AF4/FMR2 FAMILY MEMBER; 1.
DR   PANTHER; PTHR10528:SF15; AF4_FMR2 FAMILY MEMBER 4; 1.
DR   Pfam; PF05110; AF-4; 2.
DR   Pfam; PF18875; AF4_int; 1.
DR   Pfam; PF18876; AFF4_CHD; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   DOMAIN          844..1104
FT                   /note="AF4/FMR2 C-terminal homology"
FT                   /evidence="ECO:0000259|Pfam:PF18876"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          67..260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          293..641
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          673..850
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          978..1027
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..22
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        100..126
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        127..153
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..184
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..359
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        375..414
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        531..557
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        570..608
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        613..630
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        674..757
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        777..803
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        806..829
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1004..1027
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1114 AA;  120688 MW;  F60C4B0568401E65 CRC64;
     MNREDRNVLR MKERERRNQE IRQGAEAVPG SCHLFPEPYK VSSKEDKLSS RIQSMLGNYD
     EMKDVIGENT PKLVGPKATG SVSLEDRPQF PERVAGKWTP VASGSSSSSQ GPKRSGPSSK
     EGSAQRAVGN QRHERDYSGG KKASKHTAEH GKAHGPSPAK GPLRPHVAEH HSKSPREREL
     SWDSPSRIQH ASFPSGQPAG QAFPPSLMSK PGPVQQKPTA YVRPMDGQES LEPKGALESY
     GGQSHGSGVA EMKASGKSSL SKLKIPSQLL EASMSGDANC VDDILKEMTQ SLPSPLTAIQ
     TPCKPESSKF PFPAKGAQLS SFPGGGQKRH GSGSRSASHQ PKGGDGGTST NTLISDLELS
     SSEESDEEQD PKAAARNEST SNHSEGADLS RGEESSSPSE SESSSGSDSE SESSSSDSEA
     NERPHVPTPE PEPPTTNKWQ LDNWLHKVNK FSPASPADGN VPTKYKKDPR DPGSGRGYGG
     QGGSKDSGAL APNRDLRVVQ KGSEGGRGRQ RSPAQSEGCP VQRRTVGKKQ PKKNEKAPVV
     EEPKGGLKVE SETPPEIQLH RPKAATKGSR KPSIKKEARS VTRPAAEKRK GKGPTKLNKS
     REFVETDTSS DSEENESLPS SSQTPKYTES IRTPVCIPSP VEKEVLSPLS DSDEPYPIRQ
     ELLVRIDLSL LSRIPGRLHR EPEPPKVERD TTASERDGKE SQKQPGEKSS GKGKRKRKNE
     DDAVKGDKRP KLDDKSSSHH KAAGKESSKK AADRKEEPAP SPSIPGLQKM PRAEPTSRKR
     TASQSSAPVS GGNKEGSRSG KGGSSTSKHR KGEDRQAGTA KEPKEKTSKV SDGQPAALLS
     SEGSKSRRSK LTFEDRLHSA DYYLQEAKKL KHNADALMDR FEKAVYYLDA VVSFIECGNA
     LERSAQEAKS PFPMYAETVE LIKYTMKLKN YLAPDATSAD KRLAVLCLRC QALLYLRLFK
     LRKESALKYS KTLTEHLKNS LSNTQAPSPG MGSKAAGMPS PVSPKLSPGS TSSHSSGASN
     SSGSSSVTIP QRIHQMAASY VQVTSNFLYA TEVWDQAEQV AREQKEFFTE LDKVMSPLIF
     NSSSMTELVR YTRQGLHWLR LDSKPAAQRP QTPL
//