ID A0A3B3QYT3_9TELE Unreviewed; 586 AA.
AC A0A3B3QYT3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=HESX homeobox 1 {ECO:0000313|Ensembl:ENSPKIP00000010805.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000010805.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000010805.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Endosome membrane {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
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DR AlphaFoldDB; A0A3B3QYT3; -.
DR STRING; 1676925.ENSPKIP00000010805; -.
DR Ensembl; ENSPKIT00000034943.1; ENSPKIP00000010805.1; ENSPKIG00000025374.1.
DR GeneTree; ENSGT00940000156624; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR CDD; cd13247; BAR-PH_APPL; 1.
DR CDD; cd13158; PTB_APPL; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR047181; DP13A/B.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR047236; PH_DP13A/B.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR047237; PTB_APPL.
DR PANTHER; PTHR46415; ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2; 1.
DR PANTHER; PTHR46415:SF3; DCC-INTERACTING PROTEIN 13-ALPHA; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00640; PID; 1.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136}.
FT DOMAIN 377..502
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 507..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..543
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 586 AA; 66620 MW; 6C448E46CF8A5619 CRC64;
MPGIDKLPIE ETLEDSPQTR SLLGVFEEDA AAISSYTHQL FQAMQRIYDA QNELSAATHL
TSKLLRDYEK QRFPLGGDDE VMSSTLQQFA KVIDELSSCH AVLSTQLADA MMFPVTQFKE
RDLKEILTLK EVFQIASDDH DVAINKYNRL SKRKDNEKVR NEVTEDVYTS RKKQHQTMMH
YFTALNTLQY KKKIALLEPL LGYMQAQISF FKLGSENLTQ QWEDFLTDIS TSVQNVRREM
DSEVTIMQQT IQDLEQVSDI LYLPDPDPSK IPINRNLTRK AGYLNTRNKT GLVSSSWDRQ
YFFTQGGNLM SQARGDVAGG LVMDIDNCSV MAVDCEDRRF CFQITSFDGK KLVRRTNPFG
ECGDKQSEDD SILHQLYIVH FLGSMEVRAM DNSDVIYETM RQILAARAIH NIFRMTESHM
LVTCDCLKLI DPQTQVTRLR FPLSSVVLCA SHQENKRLFG FVLQTGAGQT DDQPATVCYI
FESNNDGEKI CDSIGLAKQI AYHSEMGRKA SEKRRELDKA KEKQQEELNK QKQIEKDLEE
QSRLIAASSR PGATGNPDMQ FLVLSNSQSE DGEVGEDGQK KAESEA
//
