ID   A0A3B3R663_9TELE        Unreviewed;      4347 AA.
AC   A0A3B3R663;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=HYDIN axonemal central pair apparatus protein {ECO:0000313|Ensembl:ENSPKIP00000013156.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000013156.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000013156.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   STRING; 1676925.ENSPKIP00000013156; -.
DR   Ensembl; ENSPKIT00000037572.1; ENSPKIP00000013156.1; ENSPKIG00000000601.1.
DR   GeneTree; ENSGT00940000163228; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 21.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR031549; ASH.
DR   InterPro; IPR033305; Hydin-like.
DR   InterPro; IPR033768; Hydin_ADK.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR23053; DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1; 1.
DR   PANTHER; PTHR23053:SF0; HYDROCEPHALUS-INDUCING PROTEIN HOMOLOG; 1.
DR   Pfam; PF15780; ASH; 1.
DR   Pfam; PF17213; Hydin_ADK; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          493..591
FT                   /note="Abnormal spindle-like microcephaly-associated
FT                   protein ASH"
FT                   /evidence="ECO:0000259|Pfam:PF15780"
FT   DOMAIN          1820..1879
FT                   /note="Hydin adenylate kinase-like"
FT                   /evidence="ECO:0000259|Pfam:PF17213"
FT   REGION          1963..1982
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2519..2552
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          3196..3217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   4347 AA;  482953 MW;  6197AC578E4B0BC3 CRC64;
     MLPVMIPTQK VFNGQVNRTK HMTPSAFAHE MSLSTEQRLV NTHAMHPPRI LEVLDMSETT
     HQKFSSVDID QALFQPFPSE IVFQNYSPSE SYEVPLVLRN TDKIPRLVKV VEEESLYFKV
     ISPADMCSKV APGLASTFTV LFTPQENKDY IHRVICVTER ERFEVPIRAV GPRAILDFPD
     HLHFPVSPVK CLSQRTLLVR NVGRCEARFQ LSTRSPFSVD PPLGTLGVGQ NMQVTVDFLP
     NRVHSSPVDL PIIFVVGGVS GEDLYINIYG AAADVNVRLD RNSVLMKRTY ISMASQRCVT
     LANRSDVIVH YQWKCFGTEE EEEQLKPCSD LLRQEEKKME HFLTECTDDP AFHDHLSRLS
     STFFKQQRQL REERLVFSGD HIIISPTEGD IWPNSTAEFT VTFKPQEVKI YQQTVYCDVT
     GRESRLPLRI RGEGIGPSLE FSFDLLDVGN IFIHSKHSYE VLLSNKGYID APFHLVPPSS
     AQGRCFSFSP SEDTVPPGSC HAMVVSFSSG ILGMFSEEIL FAVEGNPQPI SLTFRGRVMG
     PTFQFSVPEL NFGDVSFGFP CTLTFQLNNT SLIPMTFNLR ILGDGSGPPS ISSMDQVSDP
     NRTDWAGHSD PTVQPAEFRL GPSSGTIQAQ GLATLCPNRV QMYNLALVVD VQGVGEEVMS
     LHIHARCVVP KVRLVKPTLE LEGCFLNHPF TMSVKLTNEA DLPACYGLLP QEHEEGPSFL
     YSCPHPRGII QPRGEAEIPL LLQAKTVGRL VVAAHIAVFG SEEPPLLIIS GVGEGPVLHI
     SPTELDFGSI PVLTDVPRTV RLLNQSPIPA PFLVRRRSQW RVEPSEGAVA PEGELQLMLV
     ACLDDTVPFH DKLHLAIEHS QARSVAVSAK GEGTTIVTDR PFLASLHTHM YCFKLTNRGR
     HSQQLYWMTD GFPPFWHRAA PPSRPGSSGG DKRLDSLHAP ECDGPVFSLE PPRLELAPGQ
     SADMVLTGAS HAPKVVQERL VCQAITGQQG GKRVILTADI TCHFVSPVLE LSAQELSFSV
     KKVPGEALLP LFQPLVLTNA SSLNLSMQLV LAKPFGLCDH LNDPSFTTSK QVTLWVRFDP
     SHGGDRVTRV AEEDLEIRHL EHPQRDSVGL RGEVHFPNLH FSSTCLDFGC ILSHTESQRR
     LTLTNRGLLP VAYRWLFLAD RRHCCIRYRI PYKAFLMLIL TIIMHYEGIY SIVYYRRDRI
     SGSCYGRWLR PILLSLFSPQ LFDCVSEAEL LLRNTGKVDF EFSVLQDQEG MTLSHLQPGL
     PLVLPNKGCV QANTQQKLSL YYLPGTPEVF HKAFQLQVSY FEPETVTLRG EGIFPRIFLD
     LPRSLSKIVF TLFFFYIPTC SVMLCNVHSL LIDQVLYHSQ YDALLHMEVD RLLVKENASV
     VESKDMGFRD TQTSSSSCRK SLTRFLLPEY VLDFGYVIHG DVPTHIIKAT NTGLVPVSFS
     VDHHHLAGSG FSMELDKVKN LPYCETETFE VKFDPRGANL DLGEVTAVIH IKVSGGPTVP
     VHLCAVVTMP SLTISTDTLQ FGTIQCGQCK VATVQLFNPE PVPCHWNISE KDHAKKKIDK
     HMPLYLRQKS QQEPEAQPAV FEMLPPIGVL LPGERVNVEV KFTPAEGRAY SQRLVISVTQ
     SVRRVLLLAL GEGETPQLQF SSPLLELGPA LPFSEGEEAE VLVRNPCSFP VEFYSLEFDK
     QHLEEEKILC MMKAYASDNV LLLPPRAPGE TLPPELLDFY REQNTQKPEE EGLPAAFRAV
     WMRGGTQCSQ GTASLRRTAR GSWTSHLIEV LLVGIDLGGS KESVCVGDLE LNPVSRAIAR
     HMGIDLSPAA HAARNRRGIA IIVYGAPLSG KTETAVTLAK YYGAACLSID AVVREAVSSG
     RSTAGLQARQ LCARAAQEEE AGLILAHMCE LQEQVVMRHV VCLRRAAQLS DCHRGAVFDG
     LDTTYCHSPA SALRILLRAF DNRRFIYVVN LVHTYQDFQT REKATREAEG KHGGEESPSG
     RVEIRGEWRG WRTRQWEAVP KGKEATWYVT GIYVHKVLDG LGLGPRGPPV PPPVIFSMVS
     FPLRSQGVGE QPASACFTFM VPSAAEDTSD DRREGEKDGE TLTSIPLLKV WRALLSCVSC
     RLTTFRWVIP PAGTVTLKIR FYSSVPGKFN QVLNFEVMDT RRRYQLHCRG ICGFPSINKD
     YRYTQLPGSN VSKTYIAHSG SYEFGPLLCG KNRDRYKEER YPENMETLVM HNCSPLKAEI
     HFCFQHDTKA ATFMLDPPSM TLNPNEKQGL TVWAYPTTPG LLEDSIVCCV RDNPEPAVFR
     ISCWGVRPEL DLDRKQLQFD KVLLNRKVTK SLCLRNNTLL PVAWSLSGLE ALGEEFTVSL
     DRGVIPAQSQ YSLQVHFRAS RPTSLKKAIR LEVLDADNIL GVVHTEHIQI QAEAYDVLLD
     ITFLKGSDSI LDFGTIRVSE EAKLSLALKN KGKYEVAFNK ARWRLSQVIE PIIKEGGEVI
     GIMPIKVSVQ SLFSKYSISP SETNFGPLVY GTRKCLTFTI ENRGMFEMRF SICRMPHDQS
     VPSQRKGTVT VKRTRSRESC PAKPPSGSKV RRMESIQREM GLSSQARLTM GVFSVAPCVG
     VLAPGAQQVV TVDCVADQAG SMEECIAIDI SERDPNHHPN GIPYRLAAEV CVPGVYGVAN
     VRYEHSIPFL YRDATGIYIQ DENKFIFCNV LVGQSASARF GISNTGKVPC DLSLKRTVRP
     EGNNVFELTP TKLCVPSHSR AMVVVTFSPQ SMQTYSAVFE ATSAPSTRTR ALAFELAGDG
     HLPRVTVLRP LLRTPQGGLL LQFRPVLVGR SRTLPLVLKN DGTVSAQVHI DLLDETGVFT
     LRAIAEPVED RDARASLFLT VGQQAEFEVE CRPTAEMSFE AKVQLLVVDN QYEDTMVQLV
     GDGYRDVITL DNVGSKSLPE SETADGKEAE DIHHSSQWDI LHFGVCHVAK PYQETFTMTN
     HSSSDVLRFE WPPESRQVRF SPQTGHLHMG CSKEVKVTFC SEQPVVLSAQ PVKCKLCRVV
     FTQPIDQVPD WDDRLRTIRW VDKFTRKVFL TQVIQSDPEP AHSVVENSSR ELELRINAVC
     DYARFTCKAE NIRFKDTMLY QTRIFQFQMI NSGDILLEFT WQVLMDQAGP AVGFDRGGNY
     PNLPPFSVEP SAGTINPGDS LTFCVRFSPL EVSEWEGLLI CSVPNLQDGQ GPSLAVRGRS
     LLPDCHFHLE DSDYLSGGRR NPDMQGPSGA PPRATLDPNT RVIEVSSVGI DTGTTMLVFS
     IVNPTSKSYS FMWTCEGLQD ATFKCLTPKG FIQPGKKAEV SFEFRAQDLN IAEALWTFMI
     PERNISVPFL LVGLAREPVV YMDRTHVNLG YLLMGRKVHE KVYLLNMEEV PFHFSIRQAS
     CHSEASLDTL RLEPLMGTVL PLAISFSPTQ EGPVTFNLVC DVRGKVKPLT VNVKAESFTF
     AACVQWQRKG SMLLKSSQVT VELGDKSLCH FLVSNPGKFS LDVQYELWGP PEMQRHLQVD
     PGSGIVPTGG QNSCTVTFFP LQKCVLRNTG LRIRVKNGPS FKCCFSGLAV NPSIHFSFLK
     HNFGKSFLYC AGMVPPAKTL VISNKGEQSV SLGCLYHSTV HLEVGFQPKV LLPGETMEVP
     ITFYPREVMR YKEKVFFEIN DSAKHVVEIL GQGIELKIHV EDPKDKVVNL GTLLIGQKTK
     TVIPVVNNSQ APVTFSLLLN PSVETLLDSK VEEVPVHRLV TLKSGGGRCS IELLFSPCYR
     LPPFKEELQL ECLGTVRPLL VLRGCCHGIE VQLDQKHLPF GAVAKGSRVS RRIVMSNTGD
     MGARFKWDVK AFAPVFSITP TEGYICPAML VPFDVTFAPT ELSQDLRCDN VPCAIEGGKP
     IRLTLSGSCI ATPVVKEVLH FVCQVRTEHT QAVPLSNRSS QRCTLKPVLQ GEHWSSPLTL
     VLEPGQQNKP YEITYKPLVM TGDGKKHQGS IFFSFPDGTA LLYSLLGTSE PPKAAGTVSH
     EVPCKTQFTG VLSVLNWLPR PQRFRVVVEI LKPERPDNTI TVKGLEYLDV PAATRRSYKL
     GFFSYREGNI SAKVTFGNEL TQEYLFYYVN FKATAPGVIQ MVEMVALVRQ MASATVTVEN
     PLPVGLYLTT ECRSGDVFMP PQLFVPAPLT FEYQPLRPGD STARLTLFCS ELGHFHYELL
     LRALPAPPEK PLCFRTPLGT GQYIGAKFTN YSRVKAEYTG KTDGLDYTVE KSITAPAGSQ
     AGTDVGVDVY FEPSQLGETR AALTLSSSLG GDYIFPLVGT CLPPKAQGPF TIHAGSSISI
     PFKNVFLQTT TFSFQVDNPC FTVKVTEIIR SKKTHSVVVA YESPSPQPCT GKLTVSSPRS
     EGHGQGVCWV FYLKGLSSEV GSRGKAS
//