ID   A0A3B3R6Y2_9TELE        Unreviewed;       656 AA.
AC   A0A3B3R6Y2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=T-box transcription factor 21 {ECO:0000313|Ensembl:ENSPKIP00000013421.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000013421.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000013421.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00201}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR   AlphaFoldDB; A0A3B3R6Y2; -.
DR   STRING; 1676925.ENSPKIP00000013421; -.
DR   Ensembl; ENSPKIT00000037845.1; ENSPKIP00000013421.1; ENSPKIG00000000866.1.
DR   GeneTree; ENSGT00940000166447; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0009790; P:embryo development; IEA:UniProt.
DR   GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR032385; T-box_assoc.
DR   InterPro; IPR046360; T-box_DNA-bd.
DR   InterPro; IPR036960; T-box_sf.
DR   InterPro; IPR001699; TF_T-box.
DR   InterPro; IPR018186; TF_T-box_CS.
DR   PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR   PANTHER; PTHR11267:SF125; T-BOX TRANSCRIPTION FACTOR TBX21; 1.
DR   Pfam; PF00907; T-box; 1.
DR   Pfam; PF16176; T-box_assoc; 1.
DR   PRINTS; PR00937; TBOX.
DR   SMART; SM00425; TBOX; 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
DR   PROSITE; PS01283; TBOX_1; 1.
DR   PROSITE; PS01264; TBOX_2; 1.
DR   PROSITE; PS50252; TBOX_3; 2.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00201}; Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00201}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        358..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          160..332
FT                   /note="T-box"
FT                   /evidence="ECO:0000259|PROSITE:PS50252"
FT   DOMAIN          380..397
FT                   /note="T-box"
FT                   /evidence="ECO:0000259|PROSITE:PS50252"
FT   REGION          455..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          565..656
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        620..656
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   656 AA;  72963 MW;  AC09922FF9819064 CRC64;
     MGGIGGNFYP SMLNGTETQS FEKDADINNH VYRTKDLTDL KMGIQDTRFY YQDPIQNSPD
     NLPLPYHAGQ AVAGFEAQTG RYYPHTPLTS CPFNTMRSQG RNGPGQGCAP AGGDGFATTA
     KDVYQAGGES YTSPFQHPYP RPALYPLPGL QVCGKTQALL NNFPLWAKFH KYQTEMIITK
     QGRRMFPYLS FNISSLDPSA HYNVYVDVVL ADQHHWRYQG GKWVQCGKAE GNMPGNRMYM
     HPDSPNTGAH WMRQEVSFGK LKLTNNKGSS NNVAQMIVLQ SLHKYQPRLH IVEVKEDGSD
     DPFVTSKTLT FVFPETQFIA VTAYQNADVS CLPYSPCVEY VVTSISGASS FRLLLSNYVT
     LLILFALSLS SLLLLLFIVQ ITQLKIDHNP FAKGFRDNYD ALYAPPDTER LTPSPSESQQ
     LLPGSCYHQP YLPDQYMGAL PQSRFFNRER MTIGQQPKDA SNGPHSHWYL PSQQGTGSSR
     LDFNSYEGDY SGSGFYKPFS LQGPAHSHLG YYPDHPFTSG SISTATPGVW NTGRPSPQYL
     NHSLPSKPTP GLGWYCPMPS SSSDHRLHTP SLLEPPLPPP LLQDKPKEPG DDAWLEPASV
     KSVDSADSGL YESMESKKRR VSPYASSTES SPPNRNTESN EKDNSSDAGY YGFYNN
//