ID A0A3B3REM6_9TELE Unreviewed; 730 AA.
AC A0A3B3REM6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Zinc finger CCHC domain-containing protein 8 {ECO:0000256|ARBA:ARBA00022379};
DE AltName: Full=TRAMP-like complex RNA-binding factor ZCCHC8 {ECO:0000256|ARBA:ARBA00032546};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000016355.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000016355.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the ZCCHC8 family.
CC {ECO:0000256|ARBA:ARBA00007497}.
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DR AlphaFoldDB; A0A3B3REM6; -.
DR STRING; 1676925.ENSPKIP00000016355; -.
DR Ensembl; ENSPKIT00000040844.1; ENSPKIP00000016355.1; ENSPKIG00000002641.1.
DR GeneTree; ENSGT00390000011475; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR006568; PSP_pro-rich.
DR InterPro; IPR001878; Znf_CCHC.
DR PANTHER; PTHR13316:SF0; ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR13316; ZINC FINGER, CCHC DOMAIN CONTAINING 8; 1.
DR Pfam; PF04046; PSP; 1.
DR SMART; SM00581; PSP; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 237..252
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT REGION 262..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 48..75
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 415..443
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..491
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..680
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 80923 MW; 65D20CE6EA16F4E8 CRC64;
PPSPLAEEAE LRLHQSPNMA ELDFGDGELF EQLEGGSPPR PQVCGADDGQ ALEELRQLRE
RLGEYEETID SLIAENILEL KRKLNILTRP SGINVENTRL DGPLLQILFA NNDLSKQCRQ
EIEDYIFDLI KKHESQGKEE KEKASFHVKP QASSFVLEEK EKMTSGIRKI KDAFTVVGSV
LYFTSFCLDK LGQPLLNENA QLTEGWEIPK YQQIFGQVIS LDGQELQIKE KRPKSCCFNC
GSEEHQLKDC TKPRDMNRIN EKRKEFSQGN NQSNQRYHEE EVEERFGKYK PGIVSVELLG
AMGVAQNSLP PFIYRMRQLG YPPGWLKEAE MENSGLALYD GKAEDEQFQR HKISYDVSKL
IEFPGFNVSL PANITDEWRF YGSVPMQPVH LKHNFAAYLS KSFPTPGSNC SKRSHETDST
PRRSKKRRSD FERSSDMDVD SGHSRSSDNF QFQPPLPPGS PGLDTPPPLP RGTPPATPTP
PPLPRGTPPA TPSSSGSPAL RGQAGSGLED LAVEEDGLTL EELEEQQRLI WAALASADTA
TNSDSETPNV ETPLISSSSA STPAQIDPEI EETMETERQL TANEGKDLSS PAPSDEVLVC
KDKVDEDSCV TEVGKSEVHQ GDVETAQGDV ETAQGDVETA QGDVETAQGD VETAQDEPSQ
QMEAASPRTG KQSEFTGKVT SVPHRSKFAA GIIPFEDTPE YRDVAEATGV YLRIRDLLKS
SPRSQTKNKK
//
