ID   A0A3B3RFL7_9TELE        Unreviewed;       644 AA.
AC   A0A3B3RFL7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
GN   Name=SLCO2A1 {ECO:0000313|Ensembl:ENSPKIP00000017209.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000017209.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000017209.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC       {ECO:0000256|ARBA:ARBA00009657, ECO:0000256|RuleBase:RU362056}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU362056}.
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DR   AlphaFoldDB; A0A3B3RFL7; -.
DR   Ensembl; ENSPKIT00000041717.1; ENSPKIP00000017209.1; ENSPKIG00000003227.1.
DR   GeneTree; ENSGT01080000257336; -.
DR   OrthoDB; 2874223at2759; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR002350; Kazal_dom.
DR   InterPro; IPR036058; Kazal_dom_sf.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004156; OATP.
DR   NCBIfam; TIGR00805; oat; 1.
DR   PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR   PANTHER; PTHR11388:SF14; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1; 1.
DR   Pfam; PF07648; Kazal_2; 1.
DR   Pfam; PF03137; OATP; 1.
DR   SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS51465; KAZAL_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|RuleBase:RU362056};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362056};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362056};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362056}; Transport {ECO:0000256|RuleBase:RU362056}.
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        101..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        165..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        204..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        250..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        315..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        359..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        392..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        514..532
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        553..576
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        606..629
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   DOMAIN          435..484
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
SQ   SEQUENCE   644 AA;  71351 MW;  F61F608CBE3BA364 CRC64;
     MKRLFCYYRE MEMQTKEMKK PKSSTTPLFY NIKFFVLCHG LLQLTQLLYS AYLKSSLTTI
     ERRYGLSSFS SGMISSLHEV GNTVLIIFVS YLGSWVHRPR FIGMGGLLMA LSAFLMTLPH
     FLSEPYTYSG LELGKLNICE PGRNTTDSEP CDKEGTQRLS DSGNLLLMMA SAQLLFGIGS
     VPIQPFGISY VYDFAEPGNS DLYIAILFAV SVFGPAFGYL LGSMVLRIYV DIDRMGPAKD
     LTPADPRWVG AWWMGLLISS GGLFLTSIPY FFFPKEMQRQ TAAGPKSRDL KVAQKMPEDS
     LIDFLKMFPR VFVRLLLSPF FLPLVLAQCC FSSVIAGLST FLSKFLELQY STTAAYGNLL
     IGAINLPAAA LGMLLGGIVM KWKQLSMKAV PCFSSVVLLL SIFLCLPLFF MGCSTQDIAG
     VNVDYGHQAD RRGDNGSRPF CISNCSCLDT AFNPVCGSDS REYVSPCHAG CTTYSLDPDN
     PRKAQAYSGC LCIQDGDEVG SVRPGSCTNS CPHYLLPVMF LISLAGFIAS LSHNPVYMLV
     LRTAPEEEKS FTIGVQFLIM RVLAWLPAPA IFGMVIDSSC IWWKHTCGTK LGSCGYYDNN
     LLRNRYLGLQ VALKAMGIFF LGIVSWKIWH AKDDSLEKNP EDLL
//