ID   A0A3B3RG52_9TELE        Unreviewed;      1109 AA.
AC   A0A3B3RG52;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=NACHT, LRR and PYD domains-containing protein 12-like {ECO:0000313|Ensembl:ENSPKIP00000017587.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000017587.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000017587.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3RG52; -.
DR   Ensembl; ENSPKIT00000042099.1; ENSPKIP00000017587.1; ENSPKIG00000003439.1.
DR   GeneTree; ENSGT01100000263547; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16040; SPRY_PRY_SNTX; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 6.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 7.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          202..335
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   DOMAIN          916..1109
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   REGION          59..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1109 AA;  125553 MW;  02848E020B845B7E CRC64;
     MDGLMDGYLC FLHRDQVNRC NSDPHEGDLS SIFKILEEKV QMFLKDELRR FRRYLDPNYP
     ECSETQPEED NDLDSDGQTQ KACGREGALK ITLYILRTME QNDLADMLEK RDVLSQCQPI
     VQSNLKKKCE CVFEGKAKEG QPTLLNEIYT ELYITEGRTG EVNDEHEVRQ IETASKKRLT
     EDTTVKCNDI FKPLCGREAP IRTVLSKGVA GIGKTVSVQK FILDWAEGKA NQDVHFIFTL
     PFRDLNLIKD EYSLIELLHR FIPELKSFES TELFRYKVLF IFDGLDECRL PLDFQNNESW
     FDVTKKTSLD VLLTNLIKGN LLPSALLWIT SRPAAANQIP PECVHQVTEI RGFSDAQKEE
     YFRKRFSDQS LASRIITHVK SSKSLIIMCH IPVFCWISAS VLEKLLSETD SGEIPRTLTD
     MYTHFLIFQT SLKNDKYMKN DDIKRNKYNK EFLLKLGKLA FDNLKEGNLI FYEQDLTENG
     IDVREASVHS GVCTEVFKEE YGLYQEKVYC FVHLSIQEYL AALYVFLSNS SADLLKTVVD
     EALKSKNGHL DLYLRFLLGL STDSSKSLLQ RLLAQTQTSS HNIGETAQYI KEKIQENLSP
     ERTINLFHCL NELGDNSLVE EVQRHMNSGR LSAENLSPAQ YSALAFVMLM SDEELDVFDL
     KKFVRSDKEH WRLLPVVKTS RTALLDSCDL TEQCCEVLGS ALRSNSSHLR KLDLSDNDLQ
     DSGVKLLSAG LRDSHCKLEI LRLSGCRVTE EGCSSLASAL RSNPSHLREL DLSYNHPGDS
     GVKLISALLE DPSCKLEKLK VNRCELGEKC CEALASALRS IPSLLIELDL SDNELEDSGV
     NLLSAGLGDS HCKLEILRLS GCRVTEEGCY SLASALRSNP SHLRELDLSY NHPGDSGVKL
     LSALMEDPSC KLVKLNVDHS GECRTRPGVQ KYSCQLTLDP NTAHRGLSLS EGNRKVTRGA
     EKPYPEHPER FDTEPQVLCR ESLTGRCYWE AEWDGDRAEI GVTYKGIRRK GWSADCLLGA
     NDKSWSLRGG PRSYSVWHKN EQTPIPIRPS GSRRVGVYLD WGAGALSFYR VSSDELTLLH
     RFTSSFTEPL YPGFAVYYPK CSVSWCMLG
//