ID A0A3B3RHR3_9TELE Unreviewed; 599 AA.
AC A0A3B3RHR3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000256|ARBA:ARBA00019630};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000017400.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000017400.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|RuleBase:RU004334}.
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DR STRING; 1676925.ENSPKIP00000017416; -.
DR Ensembl; ENSPKIT00000041912.1; ENSPKIP00000017400.1; ENSPKIG00000003335.1.
DR Ensembl; ENSPKIT00000041927.1; ENSPKIP00000017416.1; ENSPKIG00000003335.1.
DR GeneTree; ENSGT00950000183038; -.
DR OrthoDB; 5395768at2759; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0004879; F:nuclear receptor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06969; NR_DBD_NGFI-B; 1.
DR CDD; cd07071; NR_LBD_Nurr1; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR003070; NR4A1-3.
DR InterPro; IPR003073; NR4A2.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR24085; NUCLEAR HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24085:SF0; NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 2; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR01284; NUCLEARECPTR.
DR PRINTS; PR01287; NURRNUCRCPTR.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 261..336
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 361..596
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 599 AA; 66907 MW; 3453A4EA307E9AD0 CRC64;
MPCVQAQYGT SPQGASPASQ SYSYHAAGEY SCDFLTPEFV KFSMDLTNTE ITATTSLPSF
STFMDNYNTS YDVKPPCIYQ MPHSGEQSSI KVEDIQMHGY HQQSHIPPQS EEMMPHSGSM
YYKPSSPHTP STPNFPVQPN HMWDEPGSLH SFHQNYVATT HMIDQRKNPV SRLSLFSFKQ
SPPGTPVSSC QMRFDGPLHV PMNPDTPGAH RALESQSFAV PSAIRKQAAI GFPHSLQLGH
AHQLMDSQIP SPPSRGSPSN EGLCAVCGDN AACQHYGVRT CEGCKGFFKR TVQKNAKYVC
LANKNCPVDK RRRNRCQYCR FQKCLVVGMV KEVVRTASLK GRRGRLPSKP KSPQDPSPPS
PPVSLISALV RAHVDSNPSM SSLDYSRFQA NPDYQMTGDD TQHIQQFYDL LTGSMEIIRG
WAEKIPGFAD LPKQDQDLLF ESAFLELFVL RLAYRSNPME GKLIFCNGVV LHRLQCVRGF
GEWIDSIVEF SSNLQSMNID ISAFSCIAAL AMVTERHGLK EPKRVEELQN KIVNCLKDQV
TFNGGGLNRP NYLSKLLGKL PELRTLCTQG LQRIFYLKLE DLVPPPAIID KLFLDTLPF
//
