ID   A0A3B3RIQ4_9TELE        Unreviewed;       827 AA.
AC   A0A3B3RIQ4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Actinin alpha 3b {ECO:0000313|Ensembl:ENSPKIP00000017710.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000017710.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000017710.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the alpha-actinin family.
CC       {ECO:0000256|ARBA:ARBA00010255}.
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DR   AlphaFoldDB; A0A3B3RIQ4; -.
DR   STRING; 1676925.ENSPKIP00000017710; -.
DR   Ensembl; ENSPKIT00000042227.1; ENSPKIP00000017710.1; ENSPKIG00000003479.1.
DR   GeneTree; ENSGT00940000153968; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd21214; CH_ACTN_rpt1; 1.
DR   CDD; cd00051; EFh; 1.
DR   CDD; cd00176; SPEC; 1.
DR   Gene3D; 1.20.58.60; -; 4.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR   Gene3D; 1.10.238.10; EF-hand; 2.
DR   InterPro; IPR001589; Actinin_actin-bd_CS.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014837; EF-hand_Ca_insen.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR018159; Spectrin/alpha-actinin.
DR   InterPro; IPR002017; Spectrin_repeat.
DR   PANTHER; PTHR11915:SF432; ALPHA-ACTININ-3; 1.
DR   PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR   Pfam; PF00307; CH; 2.
DR   Pfam; PF08726; EFhand_Ca_insen; 1.
DR   Pfam; PF00435; Spectrin; 4.
DR   SMART; SM00033; CH; 1.
DR   SMART; SM00054; EFh; 2.
DR   SMART; SM01184; efhand_Ca_insen; 1.
DR   SMART; SM00150; SPEC; 3.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   SUPFAM; SSF46966; Spectrin repeat; 4.
DR   PROSITE; PS00020; ACTININ_2; 1.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          4..108
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          686..721
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          722..757
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   COILED          205..232
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          370..404
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          604..631
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   827 AA;  95431 MW;  4274706304A0C2B6 CRC64;
     MRGFFLLQTF TAWCNSHLRK AGTQIENIEE DFRNGLKLML LLEVISGERL PKPDKGKMRF
     HKIANVNKAL DFICSKGVKL VSIGAEEIVD GNVKMTLGMI WTIILRFAIQ DISVEETSAK
     EGLLLWCQRK TAPYRNVNDD PIGNLNTAFD VAEKFLDIPK MLDAEDIVNT PKPDEKAIMT
     YVSCFYHAFA GAEQAETAAN RICKVLAVNQ ENERLMEEYE KLASELLEWI RRTIPWLENR
     VAEQTMHAMQ QKLEDFRDYR RVHKPPRVQE KCQLEINFNT LQTKLRLSNR PAFMPSEGKM
     VSDIANAWKG LEQVEKGYEE WLLTEIRRLE RLDHLAEKFK QKCSLHESWT AGKEELLTQK
     DYESASLMEI RALMRKHEAF ESDLAAHQDR VEQIAAIAQE LNELDYHDAA TINARCQGIC
     DQWDNFGTLT QKRRDALERV EKLWETIDQL YLEFAKRAAP FNNWMDGAVE DLQDMFIVHS
     IEEIQSLITA HDQFKATLPE ADKERMAIMG IQNEILKIAQ TYGIKLSGIN PYTNLSHQDI
     ITKWETVKHL VPLRDQMLQE EVARQQANER LRRQFAAQAN IIGPWIQTKM EEIGRVSVDI
     AGSLEEQMNN LKTYEQNIIN YKSNIDKLEG DHQLIQEALI FDNKHTNYTM EHIRVGWEQL
     LTTIARTINE VENQILTRDA KGISQEQLNE FRASFNHFDR KRNGMMDPDD FRACLISMGY
     DLGEVEFARI MTLVDPNNTG VVTFQAFIDF MTRETAETDT AEQVMASFKI LASDKNYITV
     EELRRELPPE QAEYCISRMT KFVGTDAPTG ALDYISFSSA LYGESDL
//