ID A0A3B3RMC3_9TELE Unreviewed; 1383 AA.
AC A0A3B3RMC3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSPKIP00000018881.1};
GN Name=ZNF536 {ECO:0000313|Ensembl:ENSPKIP00000018881.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000018881.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000018881.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR Ensembl; ENSPKIT00000035709.1; ENSPKIP00000018871.1; ENSPKIG00000004247.1.
DR Ensembl; ENSPKIT00000035719.1; ENSPKIP00000018881.1; ENSPKIG00000004247.1.
DR GeneTree; ENSGT00940000156397; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 7.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45925; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR45925:SF2; ZINC FINGER PROTEIN 536; 1.
DR Pfam; PF00096; zf-C2H2; 6.
DR Pfam; PF16606; zf-C2H2_assoc; 1.
DR Pfam; PF13909; zf-H2C2_5; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 135..162
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 163..185
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 299..327
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 370..397
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 398..425
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 655..682
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 778..805
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 806..833
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 232..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 830..853
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 879..927
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 966..1018
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1153..1271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 674..702
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..751
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 891..907
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..927
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..1003
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1168..1182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1194..1224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1225..1246
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1383 AA; 150624 MW; 12F5E5804BFB3C27 CRC64;
MEESSLCLGV SSAVPEADAH LSNSVLNGRY PISQKLHQLT AQLGHAFPDL QSRQPIPEEK
AAAPLDEKSH APLASQPISS QMALLANQLN RDIDATAGLN INGRVDLQQF LNGQNLGIMS
QMNDIEDDAR KNRKYPCPLC GKRFRFNSIL SLHMRTHTGE KPFKCPYCDH RAAQKGNLKI
HLRTHKLGNL GKGRGRVREE NRLLHELEER AILRDKQMRS SLLQPRLDLK QHPQAVQHQH
PAPQSHQQQP QPTSACGLLT PAGQGPATAV AAADNPVQPS ASPKPAGPQD EQAAAPSGFR
CTFCKGKFKK REELERHIRI LHKPYKCTLC EFAASHEEDL IGHVEKAHIT AESAPGQGSG
FGGEKPANEF RCEVCGQVFS QAWFLKGHMR KHKDSFEHCC QICGRRFKEP WFLKNHMKVH
LNKLAMKSKP PDADVPLGMN SLAQEAQANL YSRYISCLQS GLLSPDKSSL SDQHQMLAKA
GIAMKEKEML GKLLSPMGGM GHGLADGEKR PLLGCLNLVP PLKSSCMERL QAAAKVAEMD
PLNSYQTWQI LGRGMAMERS FMPKEPQRGT RGPDEDLLST SMLFAKDKHN FPLLGGSDVH
KQKLHVETAQ GIKGGNGAPS CKDDGAFEGH RDFAGHCVRG PGFDCGPAGA KEKPVECPDC
GRVFRTYHQM VVHSRVHGKE PRLPEEGPQH GGGLDERRGS ASDPESQSIS RSTTPGSSNV
TEESGAGGGH SQTGSAQEDS PHPSSPSSDA GEDSGRPAGI QPPSTPQHRE RPMGSAMKDC
PYCGKTFRTS HHLKVHLRIH TGEKPYRCPH CDYAGTQSAS LKYHLERHHR ERQNGGGSSY
GHAAEHKEEH AASKSGVFVR PEVLRGVFKG VPGSMDFRGG QMLPHQWAAP GMQDRDRHGH
GHGASTENPP DHTKSQETPS AEGPASFSDL SRAYQSMVGN GMNFQGSLQA FMDSFVLSSL
KKDKEMRDKA QIQPHLGADG MEARAKRGEA AEERSDTKPT GSKPEKSQYE PLDLSVRPDS
VSLPGSAVTI QDNVAWHGCL FCPFQTSSVE LMALHLQANH LGKAKRKEGG FLDAKAGEAS
SMGKAGLMSA VLHPGYEAVS AKPEPHMDKL VQQELGKEIK GEPRGPAWSN HMESAGFQND
FFKPFGMYDA APGGLVPQGF GGSGPEQQDP LKQPSDVKNS KPSAMAELSE GHPYSDSEPT
KEREHPRSDD EFCPADRATR PGSDDDEDEA EEEDEDGEEE EMEEGEENRS MQLPVLSEDP
QKAGAARATL SPLLEKPWRG LSLLSSAGVP QGSPRAEQGR LEQQMSILSV LRAYSAENLA
AFNGLGSTSN NTGAIKRPDM PAVVHPWVRE EEAPPPPGLP ATPTPTQECH LVDTEMQEDP
LTD
//
