ID A0A3B3S3N3_9TELE Unreviewed; 1310 AA.
AC A0A3B3S3N3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Ras-associated and pleckstrin homology domains-containing protein 1-like {ECO:0000313|Ensembl:ENSPKIP00000025359.1};
GN Name=RAPH1 {ECO:0000313|Ensembl:ENSPKIP00000025359.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000025359.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000025359.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR Ensembl; ENSPKIT00000006093.1; ENSPKIP00000025359.1; ENSPKIG00000008230.1.
DR GeneTree; ENSGT00940000156552; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01259; PH_APBB1IP; 1.
DR CDD; cd16136; RA_MRL_Lpd; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR039664; GRB/APBB1IP.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR039665; PH_APBB1IP.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR11243; GROWTH FACTOR RECEPTOR-BOUND PROTEIN; 1.
DR PANTHER; PTHR11243:SF15; RAS-ASSOCIATED AND PLECKSTRIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00314; RA; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
FT DOMAIN 282..368
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 409..518
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 598..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 805..1222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1281..1310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..21
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 613..658
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..847
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 855..878
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 879..894
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 902..949
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 972..1005
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1037
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1051..1072
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1094..1108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1114..1139
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1158..1172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1178..1207
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1310 AA; 140816 MW; 4FC5B36EC7793B22 CRC64;
MEQFSDEELD HAAEEDSDKE DQDLDKMFGA WLGELDKLTK SLDDGKPEKV HKPPLIQDTN
LANFSYRFSM YNINEALSQG EPVDLDALMA DLCSIEQELS TIGKPSGGSV RLTLPGDVKG
HQRAPVSRGG GGSSGGSASS STRVSPASTL RAGSSHGRPL ASKLSLDDIT AQLERASLSM
DEAACQSPSS SALPSSSSSP ASSYSSSTMH RPPQSVRHHR RTGSAGAVSD HEIRCISRSS
RSSINSASAS SVDSLDIEKT ARPGEVDGLQ RPDPQGQGQT SSELVIRVHM SDESSKTMMV
DERQTVRQVL DNLLDKSHCG YSPDWSLVET IGELQMERIF EDHENLVENL LNWTRDSMNK
LMFIERIEKY ALFKNPQNYL LGRRETCEMA DRNKEALLEE CFGGNSVSVP EMEGVLWLKE
DGKKSWKKRY FLLRASGIYF VPKGKAKASR DLACFLQLDH VNVYYGKDYR SKYKAPTDYC
MALKHPQIQK KSQYIKYLCC DDVRTLHQWV NGIRIAKYGK QLYLNYQEAM KRTEASYDWA
SLSGSSMKSG SSSSSLPESH SNHSTQSDSG VSDTVTSGHV RSQSVVSSIF SEAWKRGTQT
EDTVKVRVDS CRGPYPPPLP QMPPVTQPPP QGRSSYPAIY PQATTPPPPA PPLPGSAHQV
APAPFTKYST ISRMQGISQA AAAAAQYRLP PLILPQQQPP APPPQSIKPA LHGINAANVP
PPPPPPPPLT MPTPGSAMAV LKLGPPSPSP QFTPPVPSQA QLPPPAVAME SGCAFPSPPL
GHPMYQPLCS NGHQDVLAQR FATLPQDFPP PLYQDESPPP PPPPALTPPP VPPQQPVVPP
PAPAKLFYGG FPPHTAPKPT SPVSPPPPAQ PLTSPPNAPP TMKKQQSYSG GGTPSQPPPT
LPKQLSFSSK APPLSIPIST APSLVKQMAN QFPGSSPPVP STLESSRYSA PLSPPVIKTK
PKWQPVGQTQ QQSPEFPPPP PESSLGFPPP PEPDTSTPLP HPMPTLKKSP SASSAGSIGR
KPPPTPQRNS SIKSSSSLEH QEYKKVENLM SRFGQTPTPT LPAPSSGSPS KEPLSAPPGL
PKPGKLNLAN LPPALQGQVG QHTEPSGDFP SPPQDFDYFP PPPPDSELFP PPPPVADTPS
GAPRVAVVNP QPQVPSAPAP ATWSQSSMKK KTPPPTLARR STPTPEPQLI SPPGQQGHPP
HLASPLPPTS PKGTLSLQPN FLEDLNRTLK RKSVTRHGSL TSARISTKLE PVATMDDMAL
LPPPPPELLL DHKRKGGFAS GNISGYATLR RGPPPAPPKR DQNTKLTGEC
//
