ID   A0A3B3S404_9TELE        Unreviewed;       669 AA.
AC   A0A3B3S404;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Rhophilin, Rho GTPase binding protein 1 {ECO:0000313|Ensembl:ENSPKIP00000025258.1};
GN   Name=RHPN1 {ECO:0000313|Ensembl:ENSPKIP00000025258.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000025258.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000025258.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RHPN family.
CC       {ECO:0000256|ARBA:ARBA00010369}.
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DR   AlphaFoldDB; A0A3B3S404; -.
DR   STRING; 1676925.ENSPKIP00000025258; -.
DR   Ensembl; ENSPKIT00000005987.1; ENSPKIP00000025258.1; ENSPKIG00000008145.1.
DR   GeneTree; ENSGT00940000153837; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00136; PDZ; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 1.25.40.280; alix/aip1 like domains; 1.
DR   Gene3D; 1.10.287.160; HR1 repeat; 1.
DR   InterPro; IPR004328; BRO1_dom.
DR   InterPro; IPR038499; BRO1_sf.
DR   InterPro; IPR011072; HR1_rho-bd.
DR   InterPro; IPR036274; HR1_rpt_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR047138; RHPN1_2.
DR   PANTHER; PTHR23031; RHOPHILIN; 1.
DR   PANTHER; PTHR23031:SF6; RHOPHILIN-1; 1.
DR   Pfam; PF03097; BRO1; 1.
DR   Pfam; PF02185; HR1; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   SMART; SM01041; BRO1; 1.
DR   SMART; SM00742; Hr1; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF46585; HR1 repeat; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   PROSITE; PS51180; BRO1; 1.
DR   PROSITE; PS50106; PDZ; 1.
DR   PROSITE; PS51860; REM_1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207, ECO:0000256|SAM:Coils}.
FT   DOMAIN          6..80
FT                   /note="REM-1"
FT                   /evidence="ECO:0000259|PROSITE:PS51860"
FT   DOMAIN          91..502
FT                   /note="BRO1"
FT                   /evidence="ECO:0000259|PROSITE:PS51180"
FT   DOMAIN          516..579
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   COILED          57..84
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   669 AA;  74408 MW;  CD2AE02EE70A9605 CRC64;
     MGSACDPPQV TLRSRLQHQR ARIHQQINKE MLMRTGAENL FRATTNHKVR ETVALELSIV
     NSNLQLLKEE LEELNSNVGV YQTESEAVNV PMIPLGLKET KELDFSLPLK DFICRHYGEE
     ASQYEAEIKE LNELRQAMRT PSRNEAGLEL LIEYYNQLYF LEQRFFHPGN MLAVQFHWYD
     SLTGVPSSQR ALAFEKGSVL FNVGALYTQI GTRQNRSSAQ GIANAIDAFQ CAAGAFSYLK
     ENFSNAPSLD MSGASLGMLV RLMLAQVQEC VFERVLLLVL EDGDFPSHLQ VAQEAARQVS
     DMYWLAVQTM QQAPVKDYVP FSWATLAQVK NEHFRALSHY YAGLALCSYA REFPDMPRQL
     PDGEHVCICR PLESTEWGDG LGERMLQQLH SSKPSGPPLG MVLRDPEERR KAHLRRAVIR
     HEEAMRIHGL CRVLRKMDIL QEVLASVHKR SLSAYSQIDR EDDFCQTAEA PDIHRQPLTF
     PSPTPDFSKV RVTDLFQRLG PLSVFSARNQ WCPQRRIRLV RSDSGLGLTL RGDSPVLVAG
     VVPGGSASEA GLCEGDYIVA VNGADCKWAK HVEVVQALKA CSDGGVELGI VTMLSPKTLK
     QVRRSVFLSP CGIDESAVHL RNPTPSKGGS PTSLLTWTRK KGGAGGGVSK RLSSAFSLSF
     GAPRDAEAL
//