ID A0A3B3S489_9TELE Unreviewed; 506 AA.
AC A0A3B3S489;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=G-patch domain and KOW motifs-containing protein {ECO:0000256|RuleBase:RU369096};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000025569.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000025569.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: RNA-binding protein involved in pre-mRNA splicing.
CC {ECO:0000256|RuleBase:RU369096}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU369096}.
CC -!- SIMILARITY: Belongs to the MOS2 family. {ECO:0000256|ARBA:ARBA00010966,
CC ECO:0000256|RuleBase:RU369096}.
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DR AlphaFoldDB; A0A3B3S489; -.
DR STRING; 1676925.ENSPKIP00000025569; -.
DR Ensembl; ENSPKIT00000006306.1; ENSPKIP00000025569.1; ENSPKIG00000008382.1.
DR GeneTree; ENSGT00390000015154; -.
DR OrthoDB; 55448at2759; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:UniProtKB-UniRule.
DR CDD; cd13152; KOW_GPKOW_A; 1.
DR CDD; cd13153; KOW_GPKOW_B; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.30.30.30; -; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR041993; GPKOW_KOW1.
DR InterPro; IPR041994; GPKOW_KOW2.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR014722; Rib_uL2_dom2.
DR InterPro; IPR045166; Spp2-like.
DR InterPro; IPR026822; Spp2/MOS2_G-patch.
DR PANTHER; PTHR15818; G PATCH AND KOW-CONTAINING; 1.
DR PANTHER; PTHR15818:SF2; G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN; 1.
DR Pfam; PF12656; G-patch_2; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00739; KOW; 2.
DR PROSITE; PS50174; G_PATCH; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|RuleBase:RU369096};
KW mRNA splicing {ECO:0000256|RuleBase:RU369096};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU369096}.
FT DOMAIN 185..231
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..76
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..255
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 57667 MW; 4EAEF63E58FC068B CRC64;
MASKAGEKHG DGIDQGIVDP RCQQDGEDKK PAPISFGFSK TSSKFKTSSN LNESEREERD
YLTGVEEKEL KSTKPVEQKK ELVIPLILKN RWVRQEKPKK EPPGSKDCPP SQELDSVESQ
AVKELVEESR RQLDQWTNGT QEVLDLTIPL LMQNQVPQGF EDGDRVKVDL RPESSTDADY
ESVPVEAYGL AMLKGMGWKE DEGIGRTFKQ VVKPIEHQLR PKGLGLGADR SALKDLEPSG
PRRPPKPGED RSEEELVLAP GASVLLEAGA HKDHYGKVEG MDPDNARVMV KLAIGGKTVT
VSQYNIRLVG RKEYDRNAKD LSRHSKAHME AEKEKERERK KEKKREERAE RNEQQQRSKE
KKDKRRHADS REKTPPVKLP RQELSTPTWL QRDLRVRFID KTFKGGKYYN SKMTVEDVLT
PRTCVCRTEE GRLLDGVKQE MLETMVPKSE SDCIMVVLGE HRGQVGRILQ RDKERCRAMV
QLDRHEEKIY TLDYDSICHY VGGGYA
//
