ID A0A3B3S4V1_9TELE Unreviewed; 654 AA.
AC A0A3B3S4V1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=CBFA2/RUNX1 partner transcriptional co-repressor 3 {ECO:0000313|Ensembl:ENSPKIP00000025737.1};
GN Name=CBFA2T3 {ECO:0000313|Ensembl:ENSPKIP00000025737.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000025737.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000025737.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3S4V1; -.
DR Ensembl; ENSPKIT00000006480.1; ENSPKIP00000025737.1; ENSPKIG00000008424.1.
DR GeneTree; ENSGT00950000183176; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 6.10.250.230; -; 1.
DR Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR InterPro; IPR013289; CBFA2T1/2/3.
DR InterPro; IPR014896; NHR2.
DR InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR InterPro; IPR003894; TAFH_NHR1.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR10379; MTG8 ETO EIGHT TWENTY ONE PROTEIN; 1.
DR PANTHER; PTHR10379:SF6; PROTEIN CBFA2T3; 1.
DR Pfam; PF08788; NHR2; 1.
DR Pfam; PF07531; TAFH; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR PRINTS; PR01875; ETOFAMILY.
DR SMART; SM00549; TAFH; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF158553; TAFH domain-like; 1.
DR PROSITE; PS51119; TAFH; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 149..244
FT /note="TAFH"
FT /evidence="ECO:0000259|PROSITE:PS51119"
FT DOMAIN 542..578
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 1..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 426..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 481..523
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..610
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 654 AA; 71259 MW; 7228C584A9967FAA CRC64;
MLQDPTPAQT TQAGRPVGSA TGVASPSRPP PSPGGGARND LVCPLRDLTP SHLSAGSAEQ
KVGTMPDSPA DVKTQPRLTP PTMPPPPPAV SQAANRNASF TPTTMLNGSG HSPTALNGAP
STPNGFSNGP AMSSTASLST QQLPPACGAR QLCKLKRFLT TLQQFGNDIS PEIGERVRSL
VLGLVNSTLT IEEFHGKLQE ATNFPLRPFV IPFLKANLPL LQRELLHCAR MAKQTPAQYL
AQHEQLLLDA NASSPLDSSE ILLEINEHGK RKTPDRTKDN GADREGLHAE HLAKRPCTVS
PSQRYSPSGS LTSHPPPNGL THPTHYRLED MALAHHYRDA YRHTEHREAR ERHRQTAVHG
ARQEEVIDHR LTDREWAEEW KHLDNLLNCI MDMVEKTRRS LTVLRRCQEA DREEMNHWIR
RYSDVEDMKK GGSSAQRLPH LSPPPPHNSN TPNKIHRDFL HRPPSGYLPE EIWRKAEEAV
NEVKRQAMLE LQKAVSDAER KAHEMISTER SKMERALAEA KRQASEDALT VINQQEDSSE
SCWNCGRKAS ETCSGCNTAR YCGSFCQHRD WEKHHHVCGQ SLPGATSSSS SSSSGAPPTH
SESNPPASLS LSGPAAGAGG GSNSTTASPK EASSSSASRS TTPATPALLD SASR
//
