ID A0A3B3SEL3_9TELE Unreviewed; 429 AA.
AC A0A3B3SEL3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Bone morphogenetic protein 2-like {ECO:0000313|Ensembl:ENSPKIP00000028873.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000028873.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000028873.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR AlphaFoldDB; A0A3B3SEL3; -.
DR STRING; 1676925.ENSPKIP00000028873; -.
DR Ensembl; ENSPKIT00000009661.1; ENSPKIP00000028873.1; ENSPKIG00000010340.1.
DR GeneTree; ENSGT00940000155666; -.
DR OrthoDB; 2912454at2759; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF246; BONE MORPHOGENETIC PROTEIN 16; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..429
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017217547"
FT DOMAIN 310..429
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 267..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 429 AA; 47897 MW; 16C4DF3805B11D1F CRC64;
MSPANLVVLM VLLLPQVLSG HQGGAISPGG DPLPPREASL AQSIQNLLLT RLGLRSRPTP
RPGAPVPRYL LDLYRFHKQQ YHLVEDPHFS FPVQHVQGAN TVRSFHHMES SDALPLTLNV
TQASDVIRIR FNISSIPVDE RVTSAELRLL HGVGKRSAGN HRVSLFLSGD HSDLGTTLLE
SRCLIQSGNS ESSSWESFTL NSDLIESASD RTGLLEFVIE VTPLNGSLTS GQELRRERLR
VRRAAGQNEP SWAQERPLLV TYSHDGRGQT LARSAGRQEG GKKLKRRHRK GRDGNGDWGR
GRRQGRREQR VKRNGGKGAR LQQLSRNLCR RYPLYVDFSD VGWNKWIVAP SGYHAYFCLG
ECRFPLADHM NSSSHAMVQT LVNSVNRDVP RPCCVPTSLS PIAMLYLDQQ DHVVLKNYEE
MVVEGCGCR
//
