ID A0A3B3SJ97_9TELE Unreviewed; 490 AA.
AC A0A3B3SJ97;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Ring finger protein 180 {ECO:0000313|Ensembl:ENSPKIP00000030423.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000030423.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000030423.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3SJ97; -.
DR STRING; 1676925.ENSPKIP00000030423; -.
DR Ensembl; ENSPKIT00000011240.1; ENSPKIP00000030423.1; ENSPKIG00000011285.1.
DR GeneTree; ENSGT00950000182909; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR CDD; cd16554; RING-HC_RNF180; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR033263; RNF180.
DR InterPro; IPR045790; RNF180_C.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR46717; E3 UBIQUITIN-PROTEIN LIGASE RNF180; 1.
DR PANTHER; PTHR46717:SF1; E3 UBIQUITIN-PROTEIN LIGASE RNF180; 1.
DR Pfam; PF19332; RNF180_C; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 463..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 329..371
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 204..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..279
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..294
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 490 AA; 55149 MW; B182349D3AE53E24 CRC64;
MLLSPYSRLL NKSDHHVNTE CMSVYLSVYP CWSVSLSVCV SAAVCLSLSL SSSVILCVSS
FVSPSPGQLS LHTRQSAICL VSSLLQTLPG LLFWNHKRLC HCSLVLSRPP LLHKAHIVPP
VVLQAQWTRG KLLCPHCGAR LGGFDFMRQA SCPCGHQLTV HLSESRVDRD HRLTVFLSDT
WAYRSRRQPR ELRPSQEVCH LEGLGLPEKT QSTAPQLMGG AEPSGLAEPS PTYRITGEET
SPDALATTTI RQQLPSRSSM EGGGREGEEP GERRPGRRER KYMRSLRRKR RGRERGLQSQ
WLEQQEGSTG NASSSDEDEA GRDREGLTCA VCLDIYFNPY MCRPCGHVFC EPCLRTLARS
CPSNTPCPLC RTPISHVCFQ IELSHTSQSC FPEEYISRRQ NFQKDNCAQW PLPNCGKIFR
ILGGFRRRAG PVSRRQFPHG PSRLDSLAFE GDSRGRRLDM DVLVVYIYSV NWLIGFIIFC
FLCYYFFSSL
//
