ID   A0A3B3SM79_9TELE        Unreviewed;      1259 AA.
AC   A0A3B3SM79;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Ski2 like RNA helicase {ECO:0000313|Ensembl:ENSPKIP00000031453.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000031453.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000031453.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3SM79; -.
DR   STRING; 1676925.ENSPKIP00000031453; -.
DR   Ensembl; ENSPKIT00000012298.1; ENSPKIP00000031453.1; ENSPKIG00000011876.1.
DR   GeneTree; ENSGT00940000158255; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR   CDD; cd18027; DEXHc_SKIV2L; 1.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR025696; MTR4_beta-barrel.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016438; SKI2-like.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   InterPro; IPR040801; Ski2_N.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF13234; MTR4_beta-barrel; 1.
DR   Pfam; PF17911; Ski2_N; 1.
DR   PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          336..492
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          607..772
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          236..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        279..298
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1259 AA;  140707 MW;  24204F6951B4CD98 CRC64;
     MSFLVIEISP AGPDDLPLSL LEMGCSGRFE LLSNPVPKNQ TLPPLSTLPH GLPPIGPDLR
     TEVERRFLSD PEWLPIHNTD SAFQKFLRLI QRNRQIDSLL HCSPSPLHSG LSVVRDPTTG
     VLLDFNEVLL EDTSLSAKNS LSLLRAPGPP SESLRGSNTN YPFLPGGMEE LTLEQIKKKS
     EKQEEVDFEN DLLTVAPGLT AGIDFSNKEP RNSLREVNLM SLLSTFDDVI DARLHRDEEE
     EKQSAKESPK MPRTNSLEDL GIKDTVDTPS PAAASEGKKD GMTIKEGDDT ATKTEEKKRW
     AISVDISSPC DDFYKRIPDP AFKWPFELDV FQKQAILQLE SHDSVFVAAH TSAGKTVVAE
     YAIALSQKHM TRTIYTSPIK ALSNQKFRDF KHTFGDVGLL TGDVQLSPDA SCLIMTTEIL
     RSMLYNGSEV IRDLEWVIFD EVHYINDAER GVVWEEVLIM LPDHVSIILL SATVPNALEF
     SEWIGRIKKR PIYVISTVKR PVPLEHYLYT GNSTKTMKEL FLLVDSSGNF LTKGYYAAVD
     SKKERSSKHA QSFGAKGASQ NTSATQDRGV WLALLRYLSD RQQTPVVAFT FSRSRCDDNA
     RALGSMDLTT SAEKTEIHSF FQKSMSRLSG SDRQLPQILV MRDLLKRGLA VHHSGILPIL
     KEVIEMLFSR GLVKVLFATE TFAMGVNMPA RTVVFDNIRK HDGSGFRNLL PGEFIQMAGR
     AGRRGLDKTG TVIILCKSDV HDMGDLHTMM LGKPTLLQSQ FRLTYTMILN LLRVEALEVT
     DMMRRSFSES HRDTQSHEKR IRQLRQKLIS LPPLDTDAQL ADLVPLYHTL TELRVTTEAL
     QKAVMESMSG QKALSVGRVV VVNNAQHHNA LGVILQVSSD SVNRTFTTLI MCDKGREEVG
     AEPQNGVTVP LQHLYNPVLF IPDGPCSHTV QKLKMRDITA ITTKTLKVIP DRIIDNYKQR
     QQPRFRLDPP GPAVSTATQE LLRLAEANSS GITALDPVND LHLKGVEVVE GSLRLRSLQE
     SVREFSCIHS PTFSEQFSRV QERMMLQEEL DSLLYLISDQ SLTLLPEYRQ RIKVLESLNY
     VDSKGAVQLK GRVACQISRH ELLLTELLFE NTLSPLAPEE SAALLSCLVF TQNTQTCPHL
     TNTLQEGIDR VVAVAQRIGD LQVDCGLAQL AEDFVAQYKF GLTEVVYCWA RGMPFSEIAQ
     LTDVQEGTVV RCIQQLNEVL REVRQAARIV GDSVLGSKME KASLAIRRDI VFTASLYTH
//