ID A0A3B3SPV3_9TELE Unreviewed; 586 AA.
AC A0A3B3SPV3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=ATG16 autophagy related 16-like 1 (S. cerevisiae) {ECO:0000313|Ensembl:ENSPKIP00000032727.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000032727.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000032727.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat ATG16 family.
CC {ECO:0000256|ARBA:ARBA00009271}.
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DR AlphaFoldDB; A0A3B3SPV3; -.
DR STRING; 1676925.ENSPKIP00000032727; -.
DR Ensembl; ENSPKIT00000013600.1; ENSPKIP00000032727.1; ENSPKIG00000012688.1.
DR GeneTree; ENSGT00940000153936; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR CDD; cd22887; Atg16_CCD; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR045160; ATG16.
DR InterPro; IPR013923; Autophagy-rel_prot_16_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19878; AUTOPHAGY PROTEIN 16-LIKE; 1.
DR PANTHER; PTHR19878:SF6; AUTOPHAGY-RELATED PROTEIN 16-1; 1.
DR Pfam; PF08614; ATG16; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 16..206
FT /note="Autophagy-related protein 16"
FT /evidence="ECO:0000259|Pfam:PF08614"
FT REPEAT 317..358
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 361..402
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 403..444
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 461..483
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 552..586
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 202..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 586 AA; 66534 MW; 0450D029A51110DB CRC64;
MMSGAGGRTE CMWKRHIAEQ LKLRDRVQRQ AFEEIIHQYN RLLEKSDLQA VLSERLQTDK
FDLQNKQDLS PGSDSSRSDA LLQEIQQIRI RHQEELTELH KKRGELAQNV IQLNNQMQQK
DKEIQSNQVK MQEYQQRIEE LEGECRDLRT SLQELERANQ TLKDEYDALQ ITFSALEDKL
RRTTEDNQEL VSRWMAEKAQ EANRLNAENE KDCRRRQAKL QKELADAAKE PLPLDPDDDI
EVLSEEAAEV PAEGSPSRMV SRTPRWATPH ARGGLRGGAR PIDGPARLRK SPPLGVLNPA
PRCARPFRLP ETRVCLQDAH DGEVNAVRFS PGSRLLATGG MDRRVKLWEV ISGRCELKGA
LTGSNAGITC IEFDSAGSFL LASSNDFASR IWTVDDYRLR HTLTGHSGKV LSARFLLDNA
RIVSGSYDRT LKLWDLRSKV CMKTVFAGSS CNDIVCTEQC VMSGHFDKKV RFWDIRSESI
VRELELMGRV TSLDLNHDRT ELLTCSRDDL VKIIDLRCNA VRQTFSSQGF KCGSDWTRVA
FRLSCFTSHR PLLSRSTAIN AVSWSPSGTH VVSVEKGSRV VLWSDM
//
